Results 201 to 210 of about 212,176 (344)

Automated patch-clamp recordings for detecting activators and inhibitors of the epithelial sodium channel (ENaC). [PDF]

Pflugers Arch
Sure F, Rapedius M, Diakov A, Bertog M, Obergrussberger A, Fertig N, Korbmacher C, Ilyaskin AV.   +7 more
europepmc   +1 more source

Two adjacent phosphorylation sites in the C-terminus of the channel's α-subunit have opposing effects on epithelial sodium channel (ENaC) activity. [PDF]

Pflugers Arch, 2022
Diakov A, Nesterov V, Dahlmann A, Korbmacher C.   +3 more
europepmc   +1 more source

Aprotinin prevents proteolytic epithelial sodium channel (ENaC) activation and volume retention in nephrotic syndrome.

Kidney International, 2018
Bernhard N. Bohnert, Martina Menacher, A. Janessa, Matthias Wörn, Anja Schork, Sophie Daiminger, H. Kalbacher, H. Häring, C. Daniel, K. Amann, Florian Sure, M. Bertog, S. Haerteis, C. Korbmacher, F. Artunc   +14 more
semanticscholar   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Renal G protein-coupled estrogen receptor 1 regulates the epithelial sodium channel promoting natriuresis to a greater extent in females. [PDF]

Am J Physiol Renal Physiol
Nasci VL, Bopassa JC, Mironova E, Rhoads M, Singh R, Buehler DP, Pollock DM, Pochynyuk OM, Stockand JD, Gohar EY.   +9 more
europepmc   +1 more source

Renal NOXA1/NOX1 Signaling Regulates Epithelial Sodium Channel and Sodium Retention in Angiotensin II-induced Hypertension. [PDF]

Antioxid Redox Signal, 2022
Vendrov AE, Stevenson MD, Lozhkin A, Hayami T, Holland NA, Yang X, Moss N, Pan H, Wickline SA, Stockand JD, Runge MS, Madamanchi NR, Arendshorst WJ.   +12 more
europepmc   +1 more source

Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner.

Cell Stem Cell, 2018
David Petrik, Michael H. Myoga, S. Grade, Niklas J. Gerkau, Melanie Pusch, C. Rose, B. Grothe, M. Götz   +7 more
semanticscholar   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Stable overexpression of the epithelial sodium channel alpha subunit reduces migration and proliferation in breast cancer cells. [PDF]

Breast Cancer Res Treat
McQueen SRA, Chin WQ, Cunliffe HE, McDonald FJ.   +3 more
europepmc   +1 more source

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel. [PDF]

Sci Rep, 2022
Zachar R, Thiel S, Hansen S, Henriksen ML, Skjoedt MO, Skjodt K, Hamzaei Z, Madsen K, Lund L, Hummler E, Svenningsen P, Jensen BL.   +11 more
europepmc   +1 more source