Results 11 to 20 of about 311,587 (357)
Glycobiology of the Epithelial to Mesenchymal Transition [PDF]
Biomedicines, 2021 Glycosylation consists in the covalent, enzyme mediated, attachment of sugar chains to proteins and lipids. A large proportion of membrane and secreted proteins are indeed glycoproteins, while glycolipids are fundamental component of cell membranes.
Michela Pucci +2 more
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Epithelial-to-Mesenchymal Transition in Pancreatic Adenocarcinoma [PDF]
The Scientific World Journal, 2010 Epithelial to mesenchymal transition (EMT) is a physiologic process that allows morphological and genetic changes of carcinoma cells from an epithelial to a mesenchymal phenotype, which is the basis of the high metastatic potential of pancreatic cancer ...
Carla Cano +2 more
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Cortactin in Epithelial–Mesenchymal Transition [PDF]
Frontiers in Cell and Developmental Biology, 2020 Cortactin, a member of the actin-binding protein family, plays an important role in cell movement involving the cytoskeleton, as cell movement mediated by cortactin may induce the epithelial-mesenchymal transition. Cortactin participates in tumor proliferation, migration, and invasion and other related disease processes by binding to different proteins
Ji Rong +3 more
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Epithelial–Mesenchymal Transition (EMT)
International Journal of Molecular Sciences, 2023 Epithelial–mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions [...]
Guidalberto Manfioletti, Monica Fedele
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Epithelial-Mesenchymal Transition [PDF]
Cancer Research, 2008 The meeting was designed to explore the intersections of signalling networks regulating and supporting epithelial-mesenchymal (EMT) and mesenchymal-epithelial transitions (MET) in development, fibrosis, and cancer.
Zavadil, Jiri +4 more
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Regulation of epithelial–mesenchymal and mesenchymal–epithelial transitions by microRNAs [PDF]
Current Opinion in Cell Biology, 2013 Epithelial-mesenchymal transition (EMT) and the reverse process, mesenchymal-epithelial transition (MET), are essential during development and in the regulation of stem cell pluripotency, yet these processes are also activated in pathological contexts, such as in fibrosis and cancer progression.
Lamouille, Samy +3 more
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Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression [PDF]
Journal of Cellular Physiology, 2007 AbstractLike a set of bookends, cellular, molecular, and genetic changes of the beginnings of life mirror those of one of the most common cause of death—metastatic cancer. Epithelial to mesenchymal transition (EMT) is an important change in cell phenotype which allows the escape of epithelial cells from the structural constraints imposed by tissue ...
Hugo, Honor +6 more
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Epithelial-mesenchymal transition
Current Issues in Pharmacy and Medical Sciences, 2023 Abstract The process of epithelial-mesenchymal transition (EMT) occurs in both physiological and pathological states, and there are increasing links between EMT and tumor progression. During this process, dynamic changes in cell organization and function occur that promote migration and invasion.
Joanna Kubik, Kamil Pawlak
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Biomarkers for epithelial-mesenchymal transitions [PDF]
Journal of Clinical Investigation, 2009 Somatic cells that change from one mature phenotype to another exhibit the property of plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this plasticity, which is easily demonstrated by studying the process of epithelial-mesenchymal transition (EMT).
Zeisberg, Michael, Neilson, Eric G.
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Epithelial-mesenchymal transition [PDF]
Journal of Cell Science, 2005 The epithelial-mesenchymal transition (EMT) is an orchestrated series of events in which cell-cell and cell-extracellular matrix (ECM) interactions are altered to release epithelial cells from the surrounding tissue, the cytoskeleton is reorganized to confer the ability to move through a three-
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