Results 31 to 40 of about 207,813 (264)

Hydrogen peroxide enhances transforming growth factor beta-2 induced epithelial–mesenchymal transition of ARPE-19 cells

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico ...
Brijesh Gelat, Pooja Rathaur, Pooja Malaviya, Binita Patel, Abhay R. Vasavada, S. R. Kaid Johar   +5 more
doaj   +1 more source

Epithelial–Mesenchymal Transition in Ovarian Carcinoma [PDF]

Frontiers in Oncology, 2012
Ovarian cancer is the most lethal gynecologic malignancy, with the majority of patients dying within 5 years of diagnosis. This poor survival of patients diagnosed with this malignancy is attributed to diagnosis at advanced stage, when the tumor has metastasized, and to chemotherapy resistance, either primary or developing along tumor progression ...
Davidson, Ben, Tropé, Claes G., Reich, Reuven   +2 more
openaire   +3 more sources

Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma [PDF]

Future Oncology, 2009
The transition of epithelial cells to a mesenchymal phenotype is of paramount relevance for embryonic development and adult wound healing. During the past decade, the epithelial-mesenchymal transition (EMT) has been increasingly recognized to occur during the progression of various carcinomas such as hepatocellular carcinoma (HCC).
van Zijl, Franziska, Zulehner, Gudrun, Petz, Michaela, Schneller, Doris, Kornauth, Christoph, Hau, Mara, Machat, Georg, Grubinger, Markus, Huber, Heidemarie, Mikulits, Wolfgang   +9 more
openaire   +2 more sources

Epithelial mesenchymal transition in human menstruation and implantation

Endocrine Journal
The endometrium during the sexual cycle undergoes detachment, tissue remodeling, and differentiation during the menstrual cycle. Localized and transient destruction and regeneration of endometrial tissue are also essential for pregnancy.
Hiroshi Uchida
doaj   +1 more source

Vitamin D and the Epithelial to Mesenchymal Transition [PDF]

Stem Cells International, 2016
Several studies support reciprocal regulation between the active vitamin D derivative 1α,25‐dihydroxyvitamin D3 (1,25(OH)2D3) and the epithelial to mesenchymal transition (EMT). Thus, 1,25(OH)2D3 inhibits EMT via the induction of a variety of target genes that encode cell adhesion and polarity proteins responsible for the epithelial phenotype and ...
Larriba, María Jesús, García de Herreros, Antonio, Muñoz, Alberto   +2 more
openaire   +5 more sources

The Epithelial-to-Mesenchymal Transition in Cancer [PDF]

Cancers, 2018
The epithelial-to-mesenchymal transition (EMT) occurs during normal embryonic development, tissue regeneration, organ fibrosis, and wound healing.[...]
openaire   +2 more sources

Form follows function: Morphological and immunohistological insights into epithelial–mesenchymal transition characteristics of tumor buds

Tumor Biology, 2017
In cancer biology, the architectural concept “form follows function” is reflected by cell morphology, migration, and epithelial–mesenchymal transition protein pattern. In vivo, features of epithelial–mesenchymal transition have been associated with tumor
Kathrin Enderle-Ammour, Moritz Bader, Theresa Dorothee Ahrens, Kai Franke, Sylvia Timme, Agnes Csanadi, Jens Hoeppner, Birte Kulemann, Jochen Maurer, Philip Reiss, Oliver Schilling, Tobias Keck, Thomas Brabletz, Elmar Stickeler, Martin Werner, Ulrich Friedrich Wellner, Peter Bronsert   +16 more
doaj   +1 more source

Lipoxin A4 ameliorates lipopolysaccharide-induced lung injury through stimulating epithelial proliferation, reducing epithelial cell apoptosis and inhibits epithelial–mesenchymal transition

Respiratory Research, 2019
Background Acute respiratory distress syndrome (ARDS) is characterized by alveolar epithelial disruption. Lipoxins (LXs), as so-called “braking signals” of inflammation, are the first mediators identified to have dual anti-inflammatory and inflammatory ...
Jing-xiang Yang, Ming Li, Xin-ou Chen, Qing-quan Lian, Qian Wang, Fang Gao, Sheng-wei Jin, Sheng-xing Zheng   +7 more
doaj   +1 more source

Pediatric cancer—pathology and microenvironment influence: a perspective into osteosarcoma and non-osteogenic mesenchymal malignant neoplasms

Discover Oncology
Pediatric cancer remains the leading cause of disease-related death among children aged 1–14 years. A few risk factors have been conclusively identified, including exposure to pesticides, high-dose radiation, and specific genetic syndromes, but the ...
Consolato M. Sergi
doaj   +1 more source

HR+HER2− breast cancers with growth factor receptor–mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells

Tumor Biology, 2017
Despite an overall good prognosis, a significant proportion of patients with hormone receptor positive human epidermal growth factor receptor 2 negative breast cancers develop distant metastases.
Krisha Desai, Radhika Aiyappa, Jyothi S Prabhu, Madhumathy G Nair, Patrick Varun Lawrence, Aruna Korlimarla, Anupama CE, Annie Alexander, Rohini S Kaluve, Suraj Manjunath, Marjorrie Correa, BS Srinath, Shekhar Patil, Anjali Kalamdani, MSN Prasad, TS Sridhar   +15 more
doaj   +1 more source