Results 11 to 20 of about 87,269,478 (305)
Epithelial-Mesenchymal Transition [PDF]
Cancer Research, 2008 The meeting was designed to explore the intersections of signalling networks regulating and supporting epithelial-mesenchymal (EMT) and mesenchymal-epithelial transitions (MET) in development, fibrosis, and cancer.
Thompson, Erik W. +9 more
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Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives [PDF]
Cancer Management and Research, 2014 Antonio Díaz-López,1 Gema Moreno-Bueno,1,2 Amparo Cano11Departamento de Bioquímica, Facultad de Medicina, Universidad Autónoma de Madrid, Instituto de Investigaciones Biomédicas “Alberto Sols” (CSIC-UAM ...
Díaz-López A +2 more
doaj +2 more sources
Mechanochemical alterations in lung cells during fibrogenesis [PDF]
, 2009 Màster en BiofísicaIdiopath pulmonary fibrosis (IPF) is a usually fatal disease associated with hardening of the lung tissue, epithelial injury and abnormal wound healing.
Pavelescu, Irina
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Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression [PDF]
Journal of Cellular Physiology, 2007 AbstractLike a set of bookends, cellular, molecular, and genetic changes of the beginnings of life mirror those of one of the most common cause of death—metastatic cancer. Epithelial to mesenchymal transition (EMT) is an important change in cell phenotype which allows the escape of epithelial cells from the structural constraints imposed by tissue ...
Hugo, Honor +6 more
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Regulation of epithelial–mesenchymal and mesenchymal–epithelial transitions by microRNAs [PDF]
Current Opinion in Cell Biology, 2013 Epithelial-mesenchymal transition (EMT) and the reverse process, mesenchymal-epithelial transition (MET), are essential during development and in the regulation of stem cell pluripotency, yet these processes are also activated in pathological contexts, such as in fibrosis and cancer progression.
Lamouille, Samy +3 more
openaire +4 more sources
Epithelial‐to‐mesenchymal transitions in the liver† [PDF]
Hepatology, 2009 The outcome of liver injury is dictated by the effectiveness of repair. Successful repair (i.e., regeneration) results in replacement of dead epithelial cells with healthy epithelial cells, and reconstructs normal hepatic structure and function. Liver regeneration is known to involve replication of surviving mature hepatocytes and bile duct cells. This
Steve S, Choi, Anna Mae, Diehl
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Epithelial-mesenchymal transition [PDF]
Journal of Cell Science, 2005 The epithelial-mesenchymal transition (EMT) is an orchestrated series of events in which cell-cell and cell-extracellular matrix (ECM) interactions are altered to release epithelial cells from the surrounding tissue, the cytoskeleton is reorganized to confer the ability to move through a three-
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Cortactin in Epithelial–Mesenchymal Transition [PDF]
Frontiers in Cell and Developmental Biology, 2020 Cortactin, a member of the actin-binding protein family, plays an important role in cell movement involving the cytoskeleton, as cell movement mediated by cortactin may induce the epithelial-mesenchymal transition. Cortactin participates in tumor proliferation, migration, and invasion and other related disease processes by binding to different proteins
Rong Ji +3 more
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Biomarkers for epithelial-mesenchymal transitions [PDF]
Journal of Clinical Investigation, 2009 Somatic cells that change from one mature phenotype to another exhibit the property of plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this plasticity, which is easily demonstrated by studying the process of epithelial-mesenchymal transition (EMT).
Zeisberg, Michael, Neilson, Eric G.
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Epithelial-mesenchymal transitions and hepatocarcinogenesis [PDF]
Journal of Clinical Investigation, 2010 Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.
Jou, Janice, Diehl, Anna Mae
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