Results 11 to 20 of about 207,813 (264)
Cortactin in Epithelial–Mesenchymal Transition [PDF]
Frontiers in Cell and Developmental Biology, 2020 Cortactin, a member of the actin-binding protein family, plays an important role in cell movement involving the cytoskeleton, as cell movement mediated by cortactin may induce the epithelial-mesenchymal transition. Cortactin participates in tumor proliferation, migration, and invasion and other related disease processes by binding to different proteins
Rong Ji +3 more
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Biomarkers for epithelial-mesenchymal transitions [PDF]
Journal of Clinical Investigation, 2009 Somatic cells that change from one mature phenotype to another exhibit the property of plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this plasticity, which is easily demonstrated by studying the process of epithelial-mesenchymal transition (EMT).
Zeisberg, Michael, Neilson, Eric G.
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Epithelial–Mesenchymal Transition (EMT)
International Journal of Molecular Sciences, 2023 Epithelial–mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions [...]
Guidalberto Manfioletti, Monica Fedele
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The basics of epithelial-mesenchymal transition [PDF]
Journal of Clinical Investigation, 2009 The origins of the mesenchymal cells participating in tissue repair and pathological processes, notably tissue fibrosis, tumor invasiveness, and metastasis, are poorly understood. However, emerging evidence suggests that epithelial-mesenchymal transitions (EMTs) represent one important source of these cells. As we discuss here, processes similar to the
Raghu, Kalluri, Robert A, Weinberg
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Mesenchymal Stem Cell-Like Properties in Fibroblasts
Cellular Physiology and Biochemistry, 2014 Fibroblasts are biologically dynamic and morphologically heterogeneous and are the most abundant connective tissue cells, with diverse structures depending on their location and activity.
Yuqiao Chang, He Li, Zhikun Guo
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Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon
World Journal of Gastroenterology, 2012 Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions are well established biological events which have an important role in not just normal tissue and organ development, but in the pathogenesis of diseases. Increasing evidence has established their presence in the human colon during colorectal carcinogenesis and cancer invasion, chronic ...
Ferenc, Sipos, Orsolya, Galamb
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Emerging roles of epithelial-mesenchymal transition in hematological malignancies
Journal of Biomedical Science, 2018 Background Epithelial-mesenchymal transition is an important process in embryonic development, fibrosis, and cancer metastasis. During the progression of epithelial cancer, activation of epithelial-mesenchymal transition is tightly associated with ...
San-Chi Chen +2 more
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Epithelial-mesenchymal transitions and hepatocarcinogenesis [PDF]
Journal of Clinical Investigation, 2010 Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.
Jou, Janice, Diehl, Anna Mae
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Epithelial–Mesenchymal Transition (EMT) 2021
International Journal of Molecular Sciences, 2022 Epithelial–mesenchymal transition (EMT) is a transdifferentiation process wherein epithelial cells acquire characteristics typical of mesenchymal cells [...]
Guidalberto Manfioletti, Monica Fedele
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A comparison of epithelial-to-mesenchymal transition and re-epithelialization [PDF]
Seminars in Cancer Biology, 2012 Wound healing and cancer metastasis share a common starting point, namely, a change in the phenotype of some cells from stationary to motile. The term, epithelial-to-mesenchymal transition (EMT) describes the changes in molecular biology and cellular physiology that allow a cell to transition from a sedentary cell to a motile cell, a process that is ...
Philip L, Leopold +2 more
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