Results 31 to 40 of about 311,587 (357)
Particle and Fibre Toxicology, 2023 Chronic exposure to silica can lead to silicosis, one of the most serious occupational lung diseases worldwide, for which there is a lack of effective therapeutic drugs and tools.
Shaoqi Yang +10 more
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Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion [PDF]
, 2018 The altered isoform switching of the fibroblast growth factor receptor 2 (FGFR2) and aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells is involved in cancer progression.
Anacker +43 more
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Epithelial-Mesenchymal Transitions in Development and Disease [PDF]
Cell, 2009 The epithelial to mesenchymal transition (EMT) plays crucial roles in the formation of the body plan and in the differentiation of multiple tissues and organs. EMT also contributes to tissue repair, but it can adversely cause organ fibrosis and promote carcinoma progression through a variety of mechanisms.
Hervé Acloque +5 more
openaire +6 more sources
Epithelial–Mesenchymal Transition (EMT) 2021
International Journal of Molecular Sciences, 2022 Epithelial–mesenchymal transition (EMT) is a transdifferentiation process wherein epithelial cells acquire characteristics typical of mesenchymal cells [...]
Guidalberto Manfioletti, Monica Fedele
openaire +3 more sources
Beni-Suef University Journal of Basic and Applied Sciences, 2023 Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico ...
Brijesh Gelat +5 more
doaj +1 more source
Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies [PDF]
Romanian Medical Journal, 2022 In the last decades understanding the relationship between the circulating platelets and the biological aggressivity of ovarian cancer gave the opportunity to researchers to introduce new therapeutic lines in ovarian cancer patients with promising ...
Irina Balescu +7 more
doaj +1 more source
[Role of epithelial-mesenchymal transition in the pathogenesis of dermal wound healing] [PDF]
Морфологія, 2015 Background. Investigation of mechanisms of wound healing remains relevant. It remains unknown the role of epithelial to mesenchymal transition in the regeneration. Epithelial to mesenchymal transition is a fundamental process, that leads epithelial cells
Volkov K.S., Kramar S.B.
doaj
Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles. [PDF]
PLoS ONE, 2016 Mesenchymal-epithelial interactions play an important role in renal tubular morphogenesis and in maintaining the structure of the kidney. The aim of this study was to investigate whether extracellular vesicles (EVs) produced by human renal proximal ...
Giulia Chiabotto +3 more
doaj +1 more source
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells [PDF]
, 2013 During embryonic development, many cells are born far from their final destination and must travel long distances. To become motile and invasive, embryonic epithelial cells undergo a process of mesenchymal conversion known as epithelial-to-mesenchymal ...
Nieto, M. Ángela
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Metabolic Plasticity and Epithelial-Mesenchymal Transition [PDF]
Journal of Clinical Medicine, 2019 A major transcriptional and phenotypic reprogramming event during development is the establishment of the mesodermal layer from the ectoderm through epithelial-mesenchymal transition (EMT). EMT is employed in subsequent developmental events, and also in many physiological and pathological processes, such as the dissemination of cancer cells through ...
Marta Cascante +3 more
openaire +5 more sources