Results 1 to 10 of about 985,623 (242)
Characterization of Lung Inflammatory Response to Aspergillus fumigatus Spores
Journal of Fungi, 2023 The airway exposure to Aspergillus fumigatus spores (AFsp) is associated with an inflammatory response, potentially leading to allergic and/or chronic pulmonary aspergillosis. The aim of our study is to better understand the host response, first in vitro,
Alexandra Bouyssi +11 more
doaj +1 more source
IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland. [PDF]
, 2013 We recently reported that the PPM1l gene encodes an endoplasmic reticulum (ER) membrane targeted protein phosphatase (named PP2Ce) with highly specific activity towards Inositol-requiring protein-1 (IRE1) and regulates the functional outcome of ER stress.
Lane, Timothy F +6 more
core +10 more sources
Genitourinary Tissue Engineering: Reconstruction and Research Models
Bioengineering, 2021 Tissue engineering is an emerging field of research that initially aimed to produce 3D tissues to bypass the lack of adequate tissues for the repair or replacement of deficient organs.
Christophe Caneparo +3 more
doaj +1 more source
Ca2+ Signaling by TRPV4 Channels in Respiratory Function and Disease
Cells, 2021 Members of the transient receptor potential (TRP) superfamily are broadly expressed in our body and contribute to multiple cellular functions. Most interestingly, the fourth member of the vanilloid family of TRP channels (TRPV4) serves different ...
Suhasini Rajan +5 more
doaj +1 more source
Irradiation Induces Epithelial Cell Unjamming
Frontiers in Cell and Developmental Biology, 2020 The healthy and mature epithelial layer is ordinarily quiescent, non-migratory, solid-like, and jammed. However, in a variety of circumstances the layer transitions to a phase that is dynamic, migratory, fluid-like and unjammed.
Michael J. O'Sullivan +7 more
doaj +1 more source
Antimicrobial peptides: Defending the mucosal epithelial barrier
Frontiers in Oral Health, 2022 The recent epidemic caused by aerosolized SARS-CoV-2 virus illustrates the importance and vulnerability of the mucosal epithelial barrier against infection.
Karen F. Johnstone, Mark C. Herzberg
doaj +1 more source
Vectorial Release of Human RNA Viruses from Epithelial Cells
Viruses, 2022 Epithelial cells are apico-basolateral polarized cells that line all tubular organs and are often targets for infectious agents. This review focuses on the release of human RNA virus particles from both sides of polarized human cells grown on transwells.
Sabine Chapuy-Regaud +5 more
doaj +1 more source
Gut Microbes, 2022 Psychological stress alters the gut microbiota and predisposes individuals to increased risk for enteric infections and chronic bowel conditions. Intestinal epithelial cells (IECs) are responsible for maintaining homeostatic interactions between the gut ...
Jacob M. Allen +10 more
doaj +1 more source
Biomedicines, 2021 Translation of novel inhalable therapies for respiratory diseases is hampered due to the lack of in vitro cell models that reflect the complexity of native tissue, resulting in many novel drugs and formulations failing to progress beyond preclinical ...
Luis Soriano +4 more
doaj +1 more source
Cells, 2021 Notch is a conserved developmental signaling pathway that is dysregulated in many cancer types, most often through constitutive activation. Tumor cells with nuclear accumulation of the active Notch receptor, NICD, generally exhibit enhanced survival ...
Allison Jevitt +6 more
doaj +1 more source