Results 1 to 10 of about 974,070 (339)

Characterization of Lung Inflammatory Response to Aspergillus fumigatus Spores

Journal of Fungi, 2023
The airway exposure to Aspergillus fumigatus spores (AFsp) is associated with an inflammatory response, potentially leading to allergic and/or chronic pulmonary aspergillosis. The aim of our study is to better understand the host response, first in vitro,
Alexandra Bouyssi, Tanguy Déméautis, Alexis Trecourt, Marie Delles, Fany Agostini, Guillaume Monneret, Olivier Glehen, Martine Wallon, Florence Persat, Gilles Devouassoux, Abderrazzak Bentaher, Jean Menotti   +11 more
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Correlation of pericoronal radiographic width with histopathology of dental follicle of impacted teeth using modified gallego's and H and E stain

Journal of the Scientific Society, 2022
Background: Dental follicles are involved the development of tooth and periodontal structures. Dental follicles are known for pleuripotency and inductive changes but are also known for origin for various pathologies.
Sandhya Tamgadge, Treville Pereira, Gokul Venkateshwar, Mandavi Waghmare, Hemant Bhutani, Charu Girotra, Siddharth Acharya   +6 more
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Modeling Notch-Induced Tumor Cell Survival in the Drosophila Ovary Identifies Cellular and Transcriptional Response to Nuclear NICD Accumulation

Cells, 2021
Notch is a conserved developmental signaling pathway that is dysregulated in many cancer types, most often through constitutive activation. Tumor cells with nuclear accumulation of the active Notch receptor, NICD, generally exhibit enhanced survival ...
Allison Jevitt, Yi-Chun Huang, Su-Mei Zhang, Deeptiman Chatterjee, Xian-Feng Wang, Geng-Qiang Xie, Wu-Min Deng   +6 more
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An autologous colonic organoid‐derived monolayer model to study immune: bacterial interactions in Crohn's disease patients

Clinical & Translational Immunology, 2022
Objectives Crohn's disease (CD) initiation and pathogenesis are believed to involve an environmental trigger in a genetically susceptible person that results in an immune response against commensal gut bacteria, leading to a compromised intestinal ...
Hamish CK Angus, Paulo CM Urbano, Gemma A Laws, Shijun Fan, Safina Gadeock, Michael Schultz, Grant Butt, Andrew J Highton, Roslyn A Kemp   +8 more
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Genitourinary Tissue Engineering: Reconstruction and Research Models

Bioengineering, 2021
Tissue engineering is an emerging field of research that initially aimed to produce 3D tissues to bypass the lack of adequate tissues for the repair or replacement of deficient organs.
Christophe Caneparo, David Brownell, Stéphane Chabaud, Stéphane Bolduc   +3 more
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Ca²⁺ Signaling by TRPV4 Channels in Respiratory Function and Disease

Cells, 2021
Members of the transient receptor potential (TRP) superfamily are broadly expressed in our body and contribute to multiple cellular functions. Most interestingly, the fourth member of the vanilloid family of TRP channels (TRPV4) serves different ...
Suhasini Rajan, Christian Schremmer, Jonas Weber, Philipp Alt, Fabienne Geiger, Alexander Dietrich   +5 more
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Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases

Frontiers in Cell and Developmental Biology, 2020
Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the ...
Anu Laulajainen-Hongisto, Anu Laulajainen-Hongisto, Sanna Katriina Toppila-Salmi, Sanna Katriina Toppila-Salmi, Annika Luukkainen, Robert Kern   +5 more
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Irradiation Induces Epithelial Cell Unjamming

Frontiers in Cell and Developmental Biology, 2020
The healthy and mature epithelial layer is ordinarily quiescent, non-migratory, solid-like, and jammed. However, in a variety of circumstances the layer transitions to a phase that is dynamic, migratory, fluid-like and unjammed.
Michael J. O'Sullivan, Jennifer A. Mitchel, Amit Das, Stephan Koehler, Herbert Levine, Dapeng Bi, Zachary D. Nagel, Jin-Ah Park   +7 more
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Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake

Journal of Lipid Research, 2008
The role of intestinal fatty acid binding protein (I-FABP) in lipid metabolism remains elusive. To address this issue, normal human intestinal epithelial cells (HIEC-6) were transfected with cDNA to overexpress I-FABP and compared with cells treated with
Alain Montoudis, Ernest Seidman, François Boudreau, Jean-François Beaulieu, Daniel Menard, Mounib Elchebly, Geneviève Mailhot, Alain-Theophile Sane, Marie Lambert, Edgard Delvin, Emile Levy   +10 more
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Antimicrobial peptides: Defending the mucosal epithelial barrier

Frontiers in Oral Health, 2022
The recent epidemic caused by aerosolized SARS-CoV-2 virus illustrates the importance and vulnerability of the mucosal epithelial barrier against infection.
Karen F. Johnstone, Mark C. Herzberg
doaj   +1 more source