Results 1 to 10 of about 911,779 (218)
Undulation Instability of Epithelial Tissues [PDF]
Treating the epithelium as an incompressible fluid adjacent to a viscoelastic stroma, we find a novel hydrodynamic instability that leads to the formation of protrusions of the epithelium into the stroma. This instability is a candidate for epithelial fingering observed in vivo.
B. Alberts+10 more
arxiv +3 more sources
Border forces and friction control epithelial closure dynamics [PDF]
Epithelization, the process whereby an epithelium covers a cell-free surface, is not only central to wound healing but also pivotal in embryonic morphogenesis, regeneration, and cancer. In the context of wound healing, the epithelization mechanisms differ depending on the sizes and geometries of the wounds as well as on the cell type while a unified ...
Cochet-Escartin, Olivier+4 more
arxiv +5 more sources
Characterization of Lung Inflammatory Response to Aspergillus fumigatus Spores
The airway exposure to Aspergillus fumigatus spores (AFsp) is associated with an inflammatory response, potentially leading to allergic and/or chronic pulmonary aspergillosis. The aim of our study is to better understand the host response, first in vitro,
Alexandra Bouyssi+11 more
doaj +1 more source
Patient Derived Colonoids as Drug Testing Platforms–Critical Importance of Oxygen Concentration
Treatment of inflammatory bowel disease (IBD) is challenging, with a series of available drugs each helping only a fraction of patients. Patients may face time-consuming drug trials while the disease is active, thus there is an unmet need for biomarkers ...
Helene Kolstad Skovdahl+26 more
doaj +1 more source
The expression and localization of V-ATPase and cytokeratin 5 during postnatal development of the pig epididymis [PDF]
Objective We examined the localization and expression of H+ pumping vacuolar ATPase (V-ATPase) and cytokeratin 5 (KRT5) in the epididymis of pigs, expressed in clear and basal cells, respectively, during postnatal development.
Yun-Jae Park+9 more
doaj +1 more source
Key Role for CRB2 in the Maintenance of Apicobasal Polarity in Retinal Pigment Epithelial Cells
Apicobasal polarity is essential for epithelial cell function, yet the roles of different proteins in its completion is not fully understood. Here, we have studied the role of the polarity protein, CRB2, in human retinal pigment epithelial (RPE) cells ...
Antonio E. Paniagua+7 more
doaj +1 more source
Psychological stress alters the gut microbiota and predisposes individuals to increased risk for enteric infections and chronic bowel conditions. Intestinal epithelial cells (IECs) are responsible for maintaining homeostatic interactions between the gut ...
Jacob M. Allen+10 more
doaj +1 more source
In postmenopausal women, a major risk factor for the development of breast cancer is obesity. In particular, the adipose tissue-derived adipokine leptin has been strongly linked to tumor cell proliferation, migration, and metastasis, but the underlying ...
Anna Acheva+4 more
doaj +1 more source
Dual oxidase 1 is dispensable during Mycobacterium tuberculosis infection in mice
IntroductionMycobacterium tuberculosis (Mtb) is the primary cause of human tuberculosis (TB) and is currently the second most common cause of death due to a singleinfectious agent.
Tuhina Gupta+6 more
doaj +1 more source
Epigenetic Regulation of Airway Epithelium Immune Functions in Asthma
Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent breathing problems resulting from airway obstruction and hyperresponsiveness.
Bilal Alashkar Alhamwe+9 more
doaj +1 more source