Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells [PDF]
, 2019 The gingival epithelium is a physical and immunological barrier to the microbiota of the oral cavity, which interact through soluble mediators with the immune cells that patrol the tissue at the gingival epithelium.
Bradshaw, David +8 more
core +4 more sources
Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake
Journal of Lipid Research, 2008 The role of intestinal fatty acid binding protein (I-FABP) in lipid metabolism remains elusive. To address this issue, normal human intestinal epithelial cells (HIEC-6) were transfected with cDNA to overexpress I-FABP and compared with cells treated with
Alain Montoudis +10 more
doaj +1 more source
Aberrant Epithelial Cell Proliferation in Peripheral Airways in Bronchiectasis
Frontiers in Cell and Developmental Biology, 2020 Dilation of bronchi and bronchioles caused by destruction and excessive epithelial remodeling is a characteristic feature of bronchiectasis. It is not known how epithelial progenitor cells contribute to these pathologic conditions in peripheral airways ...
Yang Peng +8 more
doaj +1 more source
Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway
Frontiers in Pharmacology, 2021 Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic.
Liang Wang +10 more
doaj +1 more source
Expression profiling of ascorbic acid–related transporters in human and mouse eyes [PDF]
, 2016 PURPOSE: Ascorbic acid (AsA) is an important antioxidant in the eye. Ascorbic acid is usually transported by sodium-dependent AsA transporters (SVCTs), and dehydroascorbic acid (DHA) by glucose transporters (GLUTs).
Beebe, David +10 more
core +2 more sources
Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]
, 2018 Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice +3 more
core +1 more source
Claudin-2-dependent paracellular channels are dynamically gated
eLife, 2015 Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels has never been measured.
Christopher R Weber +7 more
doaj +1 more source
The ESRP1-GPR137 axis contributes to intestinal pathogenesis
eLife, 2017 Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease.
Lukas Franz Mager +24 more
doaj +1 more source
Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles [PDF]
, 1990 Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal ...
Abrahamsson, P. +5 more
core +2 more sources
Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens. [PDF]
, 2014 The mature eye lens contains a surface layer of epithelial cells called the lens epithelium that requires a functional mitochondrial population to maintain the homeostasis and transparency of the entire lens.
Anastas, Sara +9 more
core +3 more sources