Results 11 to 20 of about 1,205,235 (393)

Functions and Diseases of the Retinal Pigment Epithelium

open access: yesFrontiers in Pharmacology, 2021
The retinal pigment epithelium is a fundamental component of the retina that plays essential roles in visual functions. Damage to the structure and function of the retinal pigment epithelium leads to a variety of retinopathies, and there is currently no ...
Song Yang, Jun Zhou, Dengwen Li
semanticscholar   +1 more source

Cellular and functional heterogeneity of the airway epithelium

open access: yesMucosal Immunology, 2021
The airway epithelium protects us from environmental insults, which we encounter with every breath. Not only does it passively filter large particles, it also senses potential danger and alerts other cells, including immune and nervous cells.
Jordan D. Davis, T. Wypych
semanticscholar   +1 more source

Evolution of cooperation in an epithelium [PDF]

open access: yesJournal of The Royal Society Interface, 2019
Cooperation is prevalent in nature, not only in the context of social interactions within the animal kingdom but also on the cellular level. In cancer, for example, tumour cells can cooperate by producing growth factors. The evolution of cooperation has traditionally been studied for well-mixed populations under the framework of evolutionary game ...
Jessie Renton, Karen M. Page
openaire   +5 more sources

Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age

open access: yesACS Chemical Neuroscience, 2020
The COVID-19 pandemic revealed that there is a loss of smell in many patients, including in infected but otherwise asymptomatic individuals. The underlying mechanisms for the olfactory symptoms are unclear.
K. Bilińska   +3 more
semanticscholar   +1 more source

Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells [PDF]

open access: yes, 2019
The gingival epithelium is a physical and immunological barrier to the microbiota of the oral cavity, which interact through soluble mediators with the immune cells that patrol the tissue at the gingival epithelium.
Bradshaw, David   +8 more
core   +4 more sources

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial composition and the mechanisms of interaction with the host that affect gut barrier function during obesity and type 2 diabetes ...
A. Everard   +11 more
semanticscholar   +1 more source

Immunomodulation of Epithelium [PDF]

open access: yesCanadian Journal of Gastroenterology, 1994
Many studies have provided evidence that the immune system is a key regulatory system of intestinal function. The interaction of immune cells with the gut epithelium plays an important role in host defence, acting to eliminate pathogens, antigens and other noxious material from the lumen of the gastrointestinal tract.
openaire   +2 more sources

Expression profiling of ascorbic acid–related transporters in human and mouse eyes [PDF]

open access: yes, 2016
PURPOSE: Ascorbic acid (AsA) is an important antioxidant in the eye. Ascorbic acid is usually transported by sodium-dependent AsA transporters (SVCTs), and dehydroascorbic acid (DHA) by glucose transporters (GLUTs).
Beebe, David   +10 more
core   +2 more sources

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.

open access: yesGastroenterology, 2011
BACKGROUND & AIMS We previously established long-term culture conditions under which single crypts or stem cells derived from mouse small intestine expand over long periods.
Toshiro Sato   +10 more
semanticscholar   +1 more source

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