Results 11 to 20 of about 582,294 (297)

Aberrant Epithelial Cell Proliferation in Peripheral Airways in Bronchiectasis

open access: yesFrontiers in Cell and Developmental Biology, 2020
Dilation of bronchi and bronchioles caused by destruction and excessive epithelial remodeling is a characteristic feature of bronchiectasis. It is not known how epithelial progenitor cells contribute to these pathologic conditions in peripheral airways ...
Yang Peng   +8 more
doaj   +1 more source

Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic.
Liang Wang   +10 more
doaj   +1 more source

Claudin-2-dependent paracellular channels are dynamically gated

open access: yeseLife, 2015
Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels has never been measured.
Christopher R Weber   +7 more
doaj   +1 more source

The ESRP1-GPR137 axis contributes to intestinal pathogenesis

open access: yeseLife, 2017
Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease.
Lukas Franz Mager   +24 more
doaj   +1 more source

Inhaled Dual Phosphodiesterase 3/4 Inhibitors for the Treatment of Patients with COPD: A Short Review

open access: yesInternational Journal of COPD, 2021
Clémence Martin,1,2 Pierre-Régis Burgel,1,2 Nicolas Roche1,2 1AP-HP Centre, Hôpital Cochin, Service de Pneumologie, Paris, France; 2Université de Paris, Institut Cochin, INSERM UMR 1016, Paris, FranceCorrespondence: Nicolas RocheService de Pneumologie ...
Martin C, Burgel PR, Roche N
doaj  

Total bladder replacement with de-epithelialized ileum: experimental study in dogs

open access: yesInternational Brazilian Journal of Urology, 2004
OBJECTIVE: To assess the value of the silicone modeler in preventing graft retraction in dogs undergoing bladder replacement with de-epithelialized ileum.
Fábio O. Vilar   +2 more
doaj   +1 more source

The Dual Role of the Airway Epithelium in Asthma: Active Barrier and Regulator of Inflammation

open access: yesCells, 2023
Chronic airway inflammation is the cornerstone on which bronchial asthma arises, and in turn, chronic inflammation arises from a complex interplay between environmental factors such as allergens and pathogens and immune cells as well as structural cells ...
Andreas Frey   +2 more
doaj   +1 more source

Engineering Airway Epithelium [PDF]

open access: yesJournal of Biomedicine and Biotechnology, 2012
Airway epithelium is constantly presented with injurious signals, yet under healthy circumstances, the epithelium maintains its innate immune barrier and mucociliary elevator function. This suggests that airway epithelium has regenerative potential (I. R. Telford and C. F. Bridgman, 1990).
John P. Soleas   +4 more
openaire   +3 more sources

Anatomy of cornea and ocular surface

open access: yesIndian Journal of Ophthalmology, 2018
Important functions of cornea in the eye include protecting the structures inside the eye, contributing to the refractive power of the eye, and focusing light rays on the retina with minimum scatter and optical degradation.
Mittanamalli S Sridhar
doaj   +1 more source

PM10 and Pseudomonas aeruginosa: effects on corneal epithelium

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
PurposeIn vivo data indicate that mouse corneas exposed to PM10 showed early perforation and thinning after infection with Pseudomonas aeruginosa. To understand the mechanisms underlying this finding, we tested the effects of PM10 and the mitochondria ...
Mallika Somayajulu   +4 more
doaj   +1 more source

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