Results 41 to 50 of about 549,660 (296)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Perbandingan Pengaruh Pendedahan Uap Bensin Jenis Pertamax Dan Premium Terhadap Gambaran Histologi Bronkus Tikus Putih (Rattus Norvegicus) Jantan

Magna Medika, 2019
Bensin yang tersedia di Indonesia adalah bensin jenis Premium dan Pertamax. Bensin Premium mengandung tetra-etil-lead yang terkandung timbal dengan nilai oktan 88 sedangkan Pertamax mengandung metil-tertil-butil-eter atau etil-tertil-butil-eter sebagai ...
Sitilia Muhartiningsih, Yuningtyaswari Yuningtyaswari   +1 more
doaj   +1 more source

Cytokine interactions with epithelium [PDF]

Canadian Journal of Gastroenterology and Hepatology, 1994
Cytokines are a family of proteins that serve as intracellular messengers within the immune system and as growth factors for several cell types. Recent studies indicate that intestinal inflammation is accompanied by increases in a wide variety of cytokines and growth factors.
openaire   +3 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Bronchial Epithelial Cells from Cystic Fibrosis Patients Express a Specific Long Non-coding RNA Signature upon Pseudomonas aeruginosa Infection

Frontiers in Cellular and Infection Microbiology, 2017
Pseudomonas aeruginosa (Pa) is the leading cause of chronic lung infection in Cystic Fibrosis (CF) patients. It is well recognized that CF epithelial cells fail to develop an appropriate response to infection, allowing bacterial colonization and a ...
Viviane Balloy, Remya Koshy, Lea Perra, Harriet Corvol, Harriet Corvol, Michel Chignard, Loïc Guillot, Vinod Scaria, Vinod Scaria   +8 more
doaj   +1 more source

Proteome changes of sheep rumen epithelium during postnatal development

Frontiers in Genetics, 2022
Background: The development of the rumen epithelium is a critical physiological challenge for sheep. However, the molecular mechanism underlying postnatal rumen development in sheep remains rarely understood.Results: Here, we used a shotgun approach and ...
Kaizhi Zheng, Liangyong Guo, Saif Ullah, Yang Cao, Xin Huang, Huili shan, Junfang Jiang, Jianliang Wu, Yongqing Jiang   +8 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake

Journal of Lipid Research, 2008
The role of intestinal fatty acid binding protein (I-FABP) in lipid metabolism remains elusive. To address this issue, normal human intestinal epithelial cells (HIEC-6) were transfected with cDNA to overexpress I-FABP and compared with cells treated with
Alain Montoudis, Ernest Seidman, François Boudreau, Jean-François Beaulieu, Daniel Menard, Mounib Elchebly, Geneviève Mailhot, Alain-Theophile Sane, Marie Lambert, Edgard Delvin, Emile Levy   +10 more
doaj