Results 41 to 50 of about 1,205,235 (393)
Irradiation Induces Epithelial Cell Unjamming
Frontiers in Cell and Developmental Biology, 2020 The healthy and mature epithelial layer is ordinarily quiescent, non-migratory, solid-like, and jammed. However, in a variety of circumstances the layer transitions to a phase that is dynamic, migratory, fluid-like and unjammed.
Michael J. O'Sullivan +7 more
doaj +1 more source
Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. [PDF]
, 2019 Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic drainage and/or bloodstream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood.
Ferreira, Fernando +14 more
core +2 more sources
Anatomy of cornea and ocular surface
Indian Journal of Ophthalmology, 2018 Important functions of cornea in the eye include protecting the structures inside the eye, contributing to the refractive power of the eye, and focusing light rays on the retina with minimum scatter and optical degradation.
Mittanamalli S Sridhar
doaj +1 more source
Three-Dimensional Explant Platform for Studies on Choroid Plexus Epithelium
Frontiers in Cellular Neuroscience, 2020 The choroid plexus (CP) plays a major role in controlling the entry of substances and immune cells into the brain as it forms the blood-cerebrospinal fluid barrier (BCSFB) in the brain ventricles.
Natalia Petersen +5 more
doaj +1 more source
Clinical & Translational Immunology, 2022 Objectives Crohn's disease (CD) initiation and pathogenesis are believed to involve an environmental trigger in a genetically susceptible person that results in an immune response against commensal gut bacteria, leading to a compromised intestinal ...
Hamish CK Angus +8 more
doaj +1 more source
Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway
Frontiers in Pharmacology, 2021 Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic.
Liang Wang +10 more
doaj +1 more source
Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]
, 2017 Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen +7 more
core +2 more sources
IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland. [PDF]
, 2013 We recently reported that the PPM1l gene encodes an endoplasmic reticulum (ER) membrane targeted protein phosphatase (named PP2Ce) with highly specific activity towards Inositol-requiring protein-1 (IRE1) and regulates the functional outcome of ER stress.
Lane, Timothy F +6 more
core +2 more sources
The Epithelial-Immune Crosstalk in Pulmonary Fibrosis
Frontiers in Immunology, 2021 Interactions between the lung epithelium and the immune system involve a tight regulation to prevent inappropriate reactions and have been connected to several pulmonary diseases.
Thomas Planté-Bordeneuve +4 more
doaj +1 more source
Tobacco exposure and somatic mutations in normal human bronchial epithelium
Nature, 2019 Tobacco smoking causes lung cancer1–3, a process that is driven by more than 60 carcinogens in cigarette smoke that directly damage and mutate DNA4,5.
Kenichi Yoshida +20 more
semanticscholar +1 more source