Results 181 to 190 of about 326,590 (304)

Evolution-Informed Viroinformatics Identifies Conserved Immune Targets with Predicted Lower Mutational Vulnerability Across Betacoronaviruses. [PDF]

Viruses
Alshammari J, Alqahtani HA, Alonaizan R, Rahman IU, Alzhrani K, Al-Hoshani N, Alwaili MA, Aziz T, Aziz T.   +8 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Epitope

Nippon Shokuhin Kagaku Kogaku Kaishi, 2006
  +5 more sources

Conformational stability and domain-specific structural features of tumor autoantigens regulate autoantibody epitope propensity. [PDF]

Protein Sci
Miyamoto A, Yamamoto R, Sakaguchi R, Kutsuma R, Mori T, Masui M, Honjo T, Futami M, Morii M, Watanabe H, Kuribayashi T, Ohashi K, Kiura K, Futami J.   +13 more
europepmc   +1 more source

Epitop [PDF]

, 2017
H. Renz, B. Gierten
openaire   +2 more sources

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Linear antibody epitope prediction using AlphaFold2. [PDF]

Elife
DeRoo J, Terry JS, Zhao N, Stasevich TJ, Snow C, Geiss BJ.   +5 more
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Immunoinformatics-Guided Design, Immunological Evaluation, and Macrophage Transcriptomic Profiling of a Multi-Epitope Vaccine Candidate Against <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>. [PDF]

Microorganisms
Luo Z, Wei Z, Xu J, Hao B, Li W, Li Y, Cheng C, Zhou X, Fan T, Zhang H, Guo J, Wang Z.   +11 more
europepmc   +1 more source