Results 191 to 200 of about 472,049 (341)

Design of antibody structure-guided epitope vaccines <i>in silico</i> to induce potent immune responses against emerging viruses. [PDF]

J Virol
Wei X-F, Zhao L, Zhao Z, Gong Y-M, Zheng Y-Y, Cheng G-F, Wang G-X, Zhu B, Kong W-G.   +8 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Nanobody-drug conjugates for targeting specific GPCR pairs. [PDF]

PLoS Biol
Huang X, Roth BL.
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Immunogenicity risk assessment of peptide-related impurities identified in generic teriparatide products. [PDF]

Front Immunol
Mattei AE, Roberts BJ, Lelias S, Miah S, Howard KE, Weaver JL, Verthelyi D, Pang ES, Edwards K, De Groot AS.   +9 more
europepmc   +1 more source

Epitope-Blocking Enzyme-Linked Immunosorbent Assays for Detection of West Nile Virus Antibodies in Domestic Mammals

, 2003
Bradley J. Blitvich, Richard A. Bowen, Nicole L. Marlenee, Roy A. Hall, Michel L. Bunning, Barry J. Beaty   +5 more
openalex   +1 more source

Temporal correlation of antibody responses to different epitopes of the human La autoantigen. [PDF]

, 1990
E. William St. Clair, James A. Burch, Michael M. Ward, Jack D. Keene, David S. Pisetsky   +4 more
openalex   +1 more source

Epitope [PDF]

, 2020
openaire   +1 more source