Results 211 to 220 of about 326,590 (304)

epiTOol: a browser-based HLA epitope (mis)matching application for small to large cohorts. [PDF]

Front Immunol
Lehmann C, Lachmann N, Doxiadis I, Loeffler-Wirth H.   +3 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Integrated immunoreactivity analysis of MHC-I epitopes derived from the Marburg virus glycoprotein. [PDF]

Front Immunol
Yang Y, Wang J, Guan E, Wei H, Sun Y, Li J, Zhang Y, Kang HB, Fang Z, Zhao J, Gao P, Yao B, Li Z, Wang Y, Zhang Y, Zhang C, Sun Y, Liu R, Yang K, Zhang X, Jiang DT.   +20 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Nomenclature, classification, and in-silico structural analysis of MSP1a variants of Anaplasma marginale. [PDF]

PLoS One
Siddiki AZ, Humaira N, Hossain NS, Akbar YB, Palit P, Phwe PE, Eva RA, Alshaar H, Tia MI, Tia MI, Marma K, Akter B, Sultana S, Alam S.   +13 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Early insights into predicted efficacy of Ebola monoclonal antibodies for the 2026 Bundibugyo virus disease outbreak. [PDF]

Nat Commun
Nabukeera KC, Luakanda-Ndelemo G, Semawule S, Ayitewala A, Adroba-Tandele P, Walakira A, Amuri-Aziza A, Jansen D, Galiwango R, Kinganda-Lusamaki E, Tebba A, Ngandu C, Ssemaganda A, Tshiani-Mbaya O, Kanyerezi S, Kyokushaba J, Akil-Bandali P, Makoha C, Oundo HR, Kimbonza S, Balinandi S, Mukadi-Bamuleka D, Nakintu V, Nsio J, Mugerwa I, Kadobera D, Euriene D, Mulangu S, Ayouba A, Eliu M, Gidudu S, Kyobe Bosa H, Wayengera M, Rimoin AW, Lubwama B, Kagirita A, Ahuka-Mundeke S, Mwamba D, Kambugu A, Kaleebu P, Happi C, Liesenborghs L, Carroll MW, Maes P, Nachega JB, Peeters M, Akilimali P, Bahatungire R, Muruta A, Kindrachuk J, Rambaut A, Kyabayinze D, Olaro C, Vercauteren K, Muyembe-Tamfum JJ, Nabadda S, Atwine D, Jjingo D, Wawina-Bokalanga T, Mbala-Kingebeni P, Ssewanyana I.   +60 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Editing around the target: epitope engineering to protect stem cell grafts. [PDF]

Blood Adv
Baek J, Casirati G, Genovese P, Gill S.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source