Results 281 to 290 of about 598,048 (347)
Characterization of <i>Shigella</i> virulence factor intracellular spread A (IcsA, or VirG) functional epitopes against <i>S. flexneri</i> 2a and <i>S. sonnei</i> invasion and adherence. [PDF]
Madhwal A, Vakamalla SSR, Li S, Zhang W.
europepmc +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Design and Evaluation of a Broadly Multivalent Adhesins-Based Multi-Epitope Fusion Antigen Vaccine Against Enterotoxigenic <i>Escherichia coli</i> Infection. [PDF]
Jia Y +10 more
europepmc +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Preclinical development of an mRNA-based multiepitope immunotherapeutic for glioblastoma. [PDF]
Lutz J +8 more
europepmc +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
A multi-epitope vaccine targeting a key virulence factor ClfA: An In-silico approach to combat Staphylococcus aureus infections. [PDF]
Nirob MNH +8 more
europepmc +1 more source

