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Allergen structures and epitopes
Allergy, 2011To cite this article: Meno KH. Allergen structures and epitopes. Allergy 2011; 66 (Suppl. 95): 19–21.AbstractHuman type 1 hypersensitivity diseases such as allergic rhinoconjunctivitis are characterized by allergen‐specific IgE antibodies produced in allergic individuals after allergen exposure.
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Distinct epitopes on amiloride
American Journal of Physiology-Cell Physiology, 1989Most Na(+)-selective transport proteins are inhibited by the drug amiloride. Studies using amiloride analogues suggest that specific regions of amiloride might participate in binding to receptors on these transport proteins. To determine whether certain domains of this drug are recognized as distinct epitopes, amiloride was coupled to albumin through ...
T R, Kleyman +4 more
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Epitope Peptides and Immunotherapy
Current Protein & Peptide Science, 2007Allergic diseases affect atopic individuals, who synthesize specific Immunoglobulins E (IgE) to environmental allergens, usually proteins or glycoproteins. These allergens include grass and tree pollens, indoor allergens such as house dust mites and animal dander, and various foods.
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Prediction of Antibody Epitopes
2015Antibodies recognize their cognate antigens in a precise and effective way. In order to do so, they target regions of the antigenic molecules that have specific features such as large exposed areas, presence of charged or polar atoms, specific secondary structure elements, and lack of similarity to self-proteins.
Morten, Nielsen, Paolo, Marcatili
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Annals of Allergy, Asthma & Immunology, 2009
To provide a general overview of T-cell epitope mapping and its relevance to physicians practicing allergy/ immunology.The PubMed database was searched for articles published from January 1, 1990, through December 31, 2008, for primary and review articles on T-cell epitope mapping. The keywords searched were CD4 T cell, major histocompatibility complex
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To provide a general overview of T-cell epitope mapping and its relevance to physicians practicing allergy/ immunology.The PubMed database was searched for articles published from January 1, 1990, through December 31, 2008, for primary and review articles on T-cell epitope mapping. The keywords searched were CD4 T cell, major histocompatibility complex
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Mapping the Epitopes of Antibodies
Biotechnology and Genetic Engineering Reviews, 2007(2007). Mapping the Epitopes of Antibodies. Biotechnology and Genetic Engineering Reviews: Vol. 24, No. 1, pp. 1-30.
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An Introduction to Epitope Mapping
2018Antibodies are protein molecules used routinely for therapeutic, diagnostic, and research purposes due to their exquisite ability to selectively recognize and bind a given antigen. The particular area of the antigen recognized by the antibody is called the epitope, and for proteinaceous antigens the epitope can be of complex nature.
Johan, Nilvebrant, Johan, Rockberg
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Molecular Biology Reports, 1992
It is important to remember that the merits of the different approaches to epitope mapping should be judged against the purpose of the study. A peptide specifically recognized by nearly all sera containing a certain autoimmune specificity [20, 21, 26], would most likely be selected for the detection of the anti-linear/continuous epitope fraction among ...
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It is important to remember that the merits of the different approaches to epitope mapping should be judged against the purpose of the study. A peptide specifically recognized by nearly all sera containing a certain autoimmune specificity [20, 21, 26], would most likely be selected for the detection of the anti-linear/continuous epitope fraction among ...
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