Results 311 to 320 of about 470,180 (352)
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EPITOPE TAGGING

Annual Review of Genetics, 1998
▪ Abstract  Epitope tagging is a recombinant DNA method by which a protein encoded by a cloned gene is made immunoreactive to a known antibody. This review discusses the major advantages and limitations of epitope tagging and describes a number of recent applications.
J W, Jarvik, C A, Telmer
openaire   +2 more sources

Mass spectrometric epitope mapping

open access: yesMass Spectrometry Reviews, 2018
© 2016 Wiley Periodicals, Inc. Mass spectrometric epitope mapping has become a versatile method to precisely determine a soluble antigen\u27s partial structure that directly interacts with an antibody in solution. Typical lengths of investigated antigens
Reham F El-Kased   +2 more
exaly   +1 more source

Non-Neutralizing Epitopes Shade Neutralizing Epitopes against Omicron in a Multiple Epitope-Based Vaccine

ACS Infectious Diseases, 2022
The ongoing coronavirus disease 2019 pandemic has raised concerns about the risk of re-infection. Non-neutralizing epitopes are one of the major reasons for antibody-dependent enhancement. Past studies on the ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have revealed an infectivity-enhancing site on the ancestral SARS-CoV-2 ...
Hua-Rui Gong   +5 more
openaire   +2 more sources

Vaccination with a novel multi-epitope ROP8 DNA vaccine against acute Toxoplasma gondii infection induces strong B and T cell responses in mice.

Comparative Immunology, Microbiology & Infectious Diseases, 2020
Rhoptry proteins (ROPs) are involved in the cell invasion and parasitophorous vacuole (PV) formation and also vital for survival of Toxoplasma gondii (T. gondii) within host cells. ROP8 have a main role during the early phase of infection and can express
M. Foroutan   +3 more
semanticscholar   +1 more source

Epitope Imprinting Technology: Progress, Applications, and Perspectives toward Artificial Antibodies

Advances in Materials, 2019
Epitope imprinting is a promising tool to generate antibody‐like specific recognition sites. Recently, because of the ease of obtaining templates, the flexibility in selecting monomers, their resistance to harsh environments, and the high specificity ...
Kaiguang Yang   +8 more
semanticscholar   +1 more source

Epitope Mapping

1998
Epitope mapping can be used to identify areas of a protein that an antibody recognizes and binds to. Monoclonal antibodies are easier to characterize, but epitope maps can also be produced for polyclonal antisera.
openaire   +3 more sources

An Overview of Epitopes and Methods for Antibody Epitope Mapping

Antibodies are protein molecules indispensable for many therapeutic, diagnostic, and research purposes due to their exquisite ability to selectively recognize and bind a given antigen. The particular area of the antigen recognized by the antibody is called the epitope, and mapping of such epitopes can provide important mechanistic insights and indicate
Johan, Nilvebrant   +3 more
openaire   +2 more sources

A question of epitope

Journal of Neuroimmunology, 1985
N, Murray   +3 more
openaire   +2 more sources

Methods of epitope mapping

Molecular Biology Reports, 1992
It is important to remember that the merits of the different approaches to epitope mapping should be judged against the purpose of the study. A peptide specifically recognized by nearly all sera containing a certain autoimmune specificity [20, 21, 26], would most likely be selected for the detection of the anti-linear/continuous epitope fraction among ...
openaire   +2 more sources

epitope3D: a machine learning method for conformational B-cell epitope prediction

Briefings Bioinform., 2021
B. M. Silva   +3 more
semanticscholar   +1 more source

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