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Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers
Science, 2004Neural progenitor cells were encapsulated in vitro within a three-dimensional network of nanofibers formed by self-assembly of peptide amphiphile molecules.
G. Silva +6 more
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Immunoglobulin Epitopes in Primates
Vox Sanguinis, 1979Abstract. Non‐human primate sera were investigated for the presence of various human immunoglobulin epitopes including allotypes of ϰ‐, γ1‐, γ2‐, γ3‐ and α2‐chains, isotypes of ϰ‐, γ1‐, γ2‐, γ3‐, γ4‐, α1‐, α2‐ and μ‐chains and iso‐allotypes. The non‐human primate sera comprised representatives of several species of apes, Old World monkeys, New World ...
Erna van Loghem, Gerda de Lange
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Annals of Allergy, Asthma & Immunology, 2009
To provide a general overview of T-cell epitope mapping and its relevance to physicians practicing allergy/ immunology.The PubMed database was searched for articles published from January 1, 1990, through December 31, 2008, for primary and review articles on T-cell epitope mapping. The keywords searched were CD4 T cell, major histocompatibility complex
Raija K. Ahmed, Markus Maeurer
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To provide a general overview of T-cell epitope mapping and its relevance to physicians practicing allergy/ immunology.The PubMed database was searched for articles published from January 1, 1990, through December 31, 2008, for primary and review articles on T-cell epitope mapping. The keywords searched were CD4 T cell, major histocompatibility complex
Raija K. Ahmed, Markus Maeurer
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Searching for peptide ligands with an epitope library.
Science, 1990Tens of millions of short peptides can be easily surveyed for tight binding to an antibody, receptor or other binding protein using an "epitope library." The library is a vast mixture of filamentous phage clones, each displaying one peptide sequence on ...
J. Scott, George P Smith
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T-Cell Epitope Processing (The Epitope Flanking Regions Matter)
2009Epitopes presented by major histocompatibility complex (MHC) class I molecules for cytotoxic T-lymphocyte (CTL) recognition are derived mainly from cytosolic proteins. Antigen presentation on the cell surface requires correct processing of epitopes by the proteasome, cytosolic and endoplasmic reticulum (ER) aminopeptidases, efficient TAP transport, and
Alejandra Nacarino Martinez +2 more
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The Structure of T-Cell Epitopes
Annual Review of Immunology, 1987We have reviewed here studies using synthetic peptides to analyze some of the properties of T-cell epitopes. Several general conclusions can be drawn. First, T-cell epitopes can usually be defined by linear sequences of about seven amino acids. However, the observation that increasing peptide length often results in increased antigenic potency has ...
and A M Livingstone, C G Fathman
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1998
Epitope mapping can be used to identify areas of a protein that an antibody recognizes and binds to. Monoclonal antibodies are easier to characterize, but epitope maps can also be produced for polyclonal antisera.
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Epitope mapping can be used to identify areas of a protein that an antibody recognizes and binds to. Monoclonal antibodies are easier to characterize, but epitope maps can also be produced for polyclonal antisera.
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Epitope Imprinting Technology: Progress, Applications, and Perspectives toward Artificial Antibodies
Advances in Materials, 2019Epitope imprinting is a promising tool to generate antibody‐like specific recognition sites. Recently, because of the ease of obtaining templates, the flexibility in selecting monomers, their resistance to harsh environments, and the high specificity ...
Kaiguang Yang +8 more
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Methods of epitope mapping [PDF]
Molecular Biology Reports, 1992 It is important to remember that the merits of the different approaches to epitope mapping should be judged against the purpose of the study. A peptide specifically recognized by nearly all sera containing a certain autoimmune specificity [20, 21, 26], would most likely be selected for the detection of the anti-linear/continuous epitope fraction among ...
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Immunoinformatics and Epitope Prediction [PDF]
, 2020 With advancements in sequencing technologies, vast amount of experimental data has accumulated. Due to rapid progress in the development of bioinformatics tools and the accumulation of data, immunoinformatics or computational immunology emerged as a special branch of bioinformatics which utilizes bioinformatics approaches for understanding and ...
Jayashree Ramana, Kusum Mehla
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