Results 211 to 220 of about 98,993 (345)

Epitope mapping via in vitro deep mutational scanning methods and its applications. [PDF]

J Biol Chem
Keen MM, Keith AD, Ortlund EA.
europepmc   +1 more source

Epitope mapping and a cocktail of monoclonal antibodies to achieve full detection coverage of potato virus Y. [PDF]

Plant Biotechnol J, 2023
Zhao CL, Zhu Q, Mu XQ, Geng C, Tian YP, Yuan XF, Yan ZY, Li XD.   +7 more
europepmc   +1 more source

Sequence Diversity, Predicted Two-Dimensional Protein Structure, and Epitope Mapping of Neisserial Opa Proteins [PDF]

, 1998
Burkhard Malorny, Giovanna Morelli, Barica Kušećek, Jan Kolberg, Mark Achtman   +4 more
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Protocol for analyzing antibody responses to glycoprotein antigens using electron-microscopy-based polyclonal epitope mapping. [PDF]

STAR Protoc, 2023
Turner HL, Jackson AM, Richey ST, Sewall LM, Antanasijevic A, Hangartner L, Ward AB.   +6 more
europepmc   +1 more source

Mapping of the high molecular weight kininogen binding site of prekallikrein. Evidence for a discontinuous epitope formed by distinct segments of the prekallikrein heavy chain

, 1993
Heiko Herwald, Willi Jahnen‐Dechent, S.A. Alla, Johann Hock, Bonno N. Bouma, Werner Müller‐Esterl   +5 more
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Mass Spectrometry-Driven Epitope Mapping: Application of Diethylpyrocarbonate Covalent Labeling for the Immunotherapeutic Target Programmed Cell Death Protein 1. [PDF]

J Am Soc Mass Spectrom
Ramanandana P, Pianpaktr P, Makjaroen J, Wongtangprasert T, Kirsch ZJ, Graban EM, Vachet RW, Somparn P, Pisitkun T, Limpikirati PK.   +9 more
europepmc   +1 more source

Epitope mapping of Acinetobacter baumannii outer membrane protein W (OmpW) and laboratory study of an OmpW-derivative peptide. [PDF]

Heliyon, 2023
Heidarinia H, Tajbakhsh E, Rostamian M, Momtaz H.   +3 more
europepmc   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source