Results 161 to 170 of about 489,867 (407)

Molecular characterization and T and B cell epitopes prediction of Mycoplasma synoviae 53 strain VlhA hemagglutinin

Genetics and Molecular Biology, 2007
Mycoplasma sinoviae is a major pathogen of poultry causing synovitis and respiratory infection. M. synoviae hemagglutinin (VlhA) is a lipoprotein encoded by related multigene families that appear to have arisen by horizontal gene transfer.
Ilana Lopes Camargo, Cristina Toscano Fonseca, Santuza Ribeiro Teixeira, Vasco Azevedo, Anderson Myioshi, Sergio Costa Oliveira   +5 more
doaj   +1 more source

AsEP: Benchmarking Deep Learning Methods for Antibody-specific Epitope Prediction [PDF]

arXiv
Epitope identification is vital for antibody design yet challenging due to the inherent variability in antibodies. While many deep learning methods have been developed for general protein binding site prediction tasks, whether they work for epitope prediction remains an understudied research question.
arxiv  

Precise epitope mapping of the murine transformation-associated protein, p53. [PDF]

, 1985
A.M. Wade-Evans, John R. Jenkins
openalex   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

epiArt: a graphical HLA eplet amino acid repertoire translation reveals the need for an epitope driven revision of allele group nomenclature

Frontiers in Genetics
IntroductionThe immune response after transplantation depends on recipient/donor HLA allele mismatches. To enhance our understanding of the relations of HLA alleles in terms of amino-acid polymorphisms and shared epitopes, we assessed pairwise sequence ...
Ilias Doxiadis, Claudia Lehmann, Nils Lachmann, Henry Loeffler-Wirth   +3 more
doaj   +1 more source

Identification of a neutralizing epitope on glycoprotein gp58 of human cytomegalovirus [PDF]

, 1989
Ursula Utz, William J. Britt, L Vugler, Michael Mach   +3 more
openalex   +1 more source

The essence of epitopes. [PDF]

The Journal of experimental medicine, 1994
L. D. Barber, Peter Parham
openaire   +3 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Comprehensive Overview of Broadly Neutralizing Antibodies against SARS-CoV-2 Variants

Viruses
Currently, SARS-CoV-2 has evolved into various variants, including the numerous highly mutated Omicron sub-lineages, significantly increasing immune evasion ability. The development raises concerns about the possibly diminished effectiveness of available
Lingyan Cui, Tingting Li, Wenhui Xue, Sibo Zhang, Hong Wang, Hongjing Liu, Ying Gu, Ningshao Xia, Shaowei Li   +8 more
doaj   +1 more source

Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4 T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection

Frontiers in Immunology, 2018
One of the major contributions to protective immunity to influenza viruses that is provided by virus-specific CD4 T cells is delivery of effector function to the infected lung.
Katherine A. Richards, Anthony T. DiPiazza, Anthony T. DiPiazza, Ajitanuj Rattan, Zackery A. G. Knowlden, Hongmei Yang, Andrea J. Sant   +6 more
doaj   +1 more source