Results 181 to 190 of about 228,208 (297)

Computational Methods in Immunoinformatics: Epitope Discovery and Diagnostic Applications. [PDF]

ACS Omega
Bulla ACS, Sbano da Silva A, Prado Sereno B, Dias MFR, Leal da Silva M.   +4 more
europepmc   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Severity-dependent IgG epitope profiling in COVID-19 reveals differential recognition of pathogen-derived antigens. [PDF]

Front Immunol
do Nascimento LA, Machado N, Borges JVDS, Fagundes BO, Bergamasco IS, Sgnotto FDR, Bachi ALL, Sato MN, Victor JR.   +8 more
europepmc   +1 more source

Hypolipidemic therapy modulates expression of apolipoprotein B epitopes on low density lipoproteins. Studies in mild to moderate hypertriglyceridemic patients

, 1987
Yosef Kleinman, Gustav Schonfeld, Dov Gavish, Y Oschry, S Eisenberg   +4 more
openalex   +1 more source

Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein [PDF]

, 1986
Sarah J. Parsons, D J McCarley, Vincent Raymond, J. Thomas Parsons   +3 more
openalex   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Correction to "Human IgE monoclonal antibodies define two unusual epitopes trapping dog allergen Can f 1 in different conformations". [PDF]

Protein Sci
europepmc   +1 more source

Computational design of an mRNA vaccine targeting antifungal-resistant Lomentospora prolificans. [PDF]

Sci Rep
Rehmani MBI, Arshad F, Khan MU, Ejaz H, Nishan U, Alotaibi A, Ullah R, Chen K, Ojha SC, Shah M.   +9 more
europepmc   +1 more source

In vitro mutagenesis of HLA-B27. Substitution of an unpaired cysteine residue in the alpha 1 domain causes loss of antibody-defined epitopes. [PDF]

, 1988
Joel D. Taurog, F A el-Zaatari
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source