Results 271 to 280 of about 489,867 (407)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Computational design of a glycosylated multi-epitope vaccine against HAsV-1 and HAsV-2 astrovirus for acute gastroenteritis. [PDF]

Sci Rep
Naveed M, Ali A, Aziz T, Ali N, Rehman HM, Khan AA, Ul Haq T, El Hadi Mohamed RA, Al-Asmari F, Alwethaynani MS, Al-Joufi FA, Fallatah D.   +11 more
europepmc   +1 more source

Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive B-cell epitopes. [PDF]

, 1989
W J Habets, Peter Sillekens, M H Hoet, George McAllister, M R Lerner, Walther J. van Venrooij   +5 more
openalex   +1 more source

Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

Proceedings of the National Academy of Sciences of the United States of America, 2016
E. Chen, N. Salinas, Yining Huang, F. Ntumngia, Manolo Plasencia, M. Gross, J. Adams, N. Tolia   +7 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

In Silico-Based Investigation of the Immunogenicity and Biochemical Attributes of <i>Toxoplasma gondii</i> Apical Membrane Antigen 1 (TgAMA1). [PDF]

J Parasitol Res
Foroutan M, Ghaffari AD, Ghaffarifar F, Karimipour-Saryazdi A, Birgani AA, Majidiani H, Cortes H, Elsheikha HM.   +7 more
europepmc   +1 more source

A poliovirus type 1 neutralization epitope is located within amino acid residues 93 to 104 of viral capsid polypeptide VP1. [PDF]

, 1983
Czeslaw Wychowski, Sylvie van der Werf, O. Siffert, R Crainic, P. Bruneau, Marc Girard   +5 more
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

B-cell epitope peptide immunotherapy alleviates chitin-binding protein-induced type 2 airway inflammation in a Blomia tropicalis-murine model. [PDF]

Respir Res
Zhang J, Luo W, Cui Y, Sun B.
europepmc   +1 more source

Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene. [PDF]

, 1989
Arthur Melms, Susanne Chrestel, Berthold Schalke, Hartmut Wekerle, Alex Mauron, Marc Ballivet, T. Barkas   +6 more
openalex   +1 more source