Results 81 to 90 of about 339,146 (175)

Spatial and temporal changes in the distribution of proteoglycans during avian neural crest development [PDF]

, 1991
In this study, we describe the distribution of various classes of proteoglycans and their potential matrix ligand, hyaluronan, during neural crest development in the trunk region of the chicken embryo.
Bronner-Fraser, Marianne, Domingo, Carmen, Krotoski, Danuta, Lallier, Thomas, Perris, Roberto, Sorrell, Michael   +5 more
core  

A novel multi-epitope mRNA vaccine against colorectal cancer: in silico design and immune efficacy profiling

Frontiers in Immunology
BackgroundColorectal cancer (CRC) has emerged as a growing global health challenge, while immunotherapy, particularly mRNA-based cancer vaccines, has emerged as a promising approach due to its ability to induce targeted immune responses with minimal ...
Lin Wang, Lin Wang, Xiaofei Zhou, Yu Wei, Jianping Lin, Jianping Lin   +5 more
doaj   +1 more source

Capturing virus evolution by proteomic bioinformatics: Hunting for characteristic mutations in the hepatitis E virus genome

Virulence, 2018
Dominik Harms, Bo Wang, C. Patrick Papp, C.-Thomas Bock   +3 more
doaj   +1 more source

Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120

Frontiers in Immunology
HIV (human immunodeficiency virus) presents a global health crisis, causing significant AIDS-related deaths and over one million new infections annually.
Muhammad Zeeshan Ahmed, Muhammad Zeeshan Ahmed, Tazeen Rao, Zeeshan Mutahir, Sarfraz Ahmed, Najeeb Ullah, Suvash Chandra Ojha   +6 more
doaj   +1 more source

An Overview of Seafood Allergens: Structure–Allergenicity Relationship and Allergenicity Elimination Processing Techniques

Foods
Seafood (fish, crustacean, and mollusk) allergy represents a critical global health issue. Food processing offers a viable strategy for allergenicity mitigation and serves as a critical intervention for seafood allergy prevention.
Yang Yang, Yehao Zhang, Xinrong He, Fei Huan, Jinli Chen, Meng Liu, Siyang He, Shinong Gu, Guangming Liu   +8 more
doaj   +1 more source

mRNA vaccine design using the proteome of Theileria annulata through immunoinformatics approaches

mSphere
Theileriosis exerts a substantial impact on ruminants, resulting in significant economic losses within the animal husbandry sector. The current vaccine, a live attenuated parasite, has several limitations that hinder effective disease control. This study
Roohollah Fattahi, Behrooz Sadeghi Kalani   +1 more
doaj   +1 more source

Editorial: Epitope Discovery and Synthetic Vaccine Design

Frontiers in Immunology, 2018
Clarisa Beatriz Palatnik-de-Sousa, Clarisa Beatriz Palatnik-de-Sousa, Irene da Silva Soares, Daniela Santoro Rosa, Daniela Santoro Rosa   +4 more
doaj   +1 more source

Identification of PD-1–PD-L1 blockade epitopes in vitro utilizing porcine immunoglobulin and heterologous Fc-fused protein

Veterinary Research
Programmed death 1 (PD-1) and its ligand, programmed death ligand 1 (PD-L1), function as pivotal immune checkpoints. Numerous studies have demonstrated the association between the malignant progression of various swine diseases and aberrant expression of
Yuwen Dong, Xin Li, Zuxin Gong, Chenchen Liu, Jiaqi Dai, Shuhuai Shen, Zhen Yang, Gongguan Liu   +7 more
doaj   +1 more source

Exploring Bioinformatics Solutions for Improved Leishmaniasis Diagnostic Tools: A Review

Molecules
Significant populations in tropical and sub-tropical locations all over the world are severely impacted by a group of neglected tropical diseases called leishmaniases.
Natáli T. Capistrano Costa, Allana M. de Souza Pereira, Cibele C. Silva, Emanuelle de Oliveira Souza, Beatriz C. de Oliveira, Luiz Felipe G. R. Ferreira, Marcelo Z. Hernandes, Valéria R. A. Pereira   +7 more
doaj   +1 more source

Epitop [PDF]

, 2017
H. Renz, B. Gierten
openaire   +2 more sources