The epitranscriptome and synaptic plasticity
RNA modifications, collectively referred to as 'the epitranscriptome,' have recently emerged as a pervasive feature of cellular mRNAs which have diverse impacts on gene expression. In the last several years, technological advances improving our ability to identify mRNA modifications, coupled with the discovery of proteins that add and remove these ...
Mathieu N Flamand, Kate D Meyer
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Getting the Entire Message: Progress in Isoform Sequencing
The advent of second-generation sequencing and its application to RNA sequencing have revolutionized the field of genomics by allowing quantification of gene expression, as well as the definition of transcription start/end sites, exons, splice sites and ...
Simon A. Hardwick +5 more
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dissertationPost-transcriptional RNA modifications provide new structural and functional features to modified RNA molecules. Extensive research in the past has resulted in isolation of over 100 distinct nucleotide modifications from different organisms ...
Vishteh, Vahid Khoddami
core
Epitranscriptomic regulations in the heart
RNA modifications affect key stages of the RNA life cycle, including splicing, export, decay, and translation. Epitranscriptomic regulations therefore significantly influence cellular physiology and pathophysiology. Here, we selected some of the most abundant modifications and reviewed their roles in the heart and in cardiovascular diseases: N6 ...
Benák, D. (Daniel) +2 more
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Epitranscriptome changes triggered by ammonium nutrition regulate the proteome response of maritime pine roots [PDF]
Francisco Ortigosa +6 more
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From RNA and its NAD-cap: Exploring T4 phage infection from an epitranscriptomic perspective [PDF]
Bacteriophages are viruses with the ability to specifically infect and kill bacteria. Bacteriophage research has shaped our understanding of fundamental biological principles and provided tools for molecular biology, but it has long been forgotten. Thus,
Wolfram-Schauerte, Maik
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Epitranscriptome marks detection and localization of RNA modifying proteins in mammalian ovarian follicles [PDF]
Karine Dubuc +7 more
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Nanopore direct RNA sequencing maps an Arabidopsis N6 methyladenosine epitranscriptome [PDF]
Matthew T Parker +8 more
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Editorial: Viruses and Epitranscriptomes: Regulation of Infection and Antiviral Response [PDF]
Ana Raquel Soares +3 more
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Weakly supervised learning of RNA modifications from low-resolution epitranscriptome data [PDF]
Daiyun Huang +5 more
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