Results 101 to 110 of about 3,547 (209)

Strategies to avoid artifacts in mass spectrometry-based epitranscriptome analyses

, 2021
In this report, we perform structure validation of recently reported RNA phosphorothioate (PT) modifications, a new set of epitranscriptome marks found in bacteria and eukaryotes including humans.
Hagelskamp, Felix, Zhang, Qinghua, Kaiser, Steffen, Liu, Lili, Cao, Bo, Gehrke, Tim Herbert, Dedon, Peter C., Ammann, Gregor, Kellner, Stefanie, Borland, Kayla, Asadi-Atoi, Paria, Byrne, Shane R., Yoluç, Yasemin, DeMott, Michael S., Brecheisen, Roland, Heiß, Matthias   +15 more
core   +1 more source

The Epitranscriptome in miRNAs: Crosstalk, Detection, and Function in Cancer

, 2022
The epitranscriptome encompasses all post-transcriptional modifications that occur on RNAs. These modifications can alter the function and regulation of their RNA targets, which, if dysregulated, result in various diseases and cancers. As with other RNAs,
Acunzo, Mario, Le, Patricia, Patrick Nana-Sinkam, del Valle-Morales, Daniel, Daniel del Valle-Morales, Giovanni Nigita, Nana-Sinkam, Patrick, Romano, Giulia, Mario Acunzo, Nigita, Giovanni, Saviana, Michela, Giulia Romano, Patricia Le, Michela Saviana   +13 more
core   +1 more source

The Epitranscriptome of Noncoding RNAs in Cancer

, 2017
The activity of RNA is controlled by different types of post-transcriptional modifications, such as the addition of methyl groups and other chemical and structural changes, that have been recently described in human cells by high-throughput sequencing ...
Pier Paolo Pandolfi, Manel Esteller
core   +1 more source

DataSheet1_The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.pdf

, 2022
The microbiome exerts profound effects on fetal development and health, yet the mechanisms underlying remain elusive. N6-methyladenosine (m6A) plays important roles in developmental regulation.
Zhuoyu Xiao (12834362), Sun Liu (474179), Zihan Wang (3129810), Laixin Xia (373554), Zengguang Li (5082146), Yuan Li (67017), Qihuan Ren (13010052), Jinru Cui (13010049), Hailan Wang (309789), Zhijian Wang (310214)   +9 more
core   +1 more source

Epitranscriptomic RNA Methylation in Plant Development and Abiotic Stress Responses

Frontiers in Plant Science, 2019
Recent advances in methylated RNA immunoprecipitation followed by sequencing and mass spectrometry have revealed widespread chemical modifications on mRNAs.
Jianzhong Hu, Stefano Manduzio, Hunseung Kang   +2 more
doaj   +1 more source

Supplement_Table_3 – Supplemental material for Predict Epitranscriptome Targets and Regulatory Functions of N6-Methyladenosine (m6A) Writers and Erasers

, 2019
Supplemental material, Supplement_Table_3 for Predict Epitranscriptome Targets and Regulatory Functions of N6-Methyladenosine (m6A) Writers and Erasers by Yiyou Song, Qingru Xu, Zhen Wei, Di Zhen, Jionglong Su, Kunqi Chen and Jia Meng in Evolutionary ...
Jionglong Su (6660905), Yiyou Song (7352294), Di Zhen (749590), Zhen Wei (203204), Jia Meng (306948), Qingru Xu (7352297), Kunqi Chen (6547694)   +6 more
core   +1 more source

Image5_The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.TIF

, 2022
The microbiome exerts profound effects on fetal development and health, yet the mechanisms underlying remain elusive. N6-methyladenosine (m6A) plays important roles in developmental regulation.
Zhuoyu Xiao (12834362), Sun Liu (474179), Zihan Wang (3129810), Laixin Xia (373554), Zengguang Li (5082146), Yuan Li (67017), Qihuan Ren (13010052), Jinru Cui (13010049), Hailan Wang (309789), Zhijian Wang (310214)   +9 more
core   +1 more source

Elucidation of the Epitranscriptomic RNA Modification Landscape of Chikungunya Virus

Viruses
The genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of viral
Belinda Baquero-Pérez, Enrico Bortoletto, Umberto Rosani, Anna Delgado-Tejedor, Rebeca Medina, Eva Maria Novoa, Paola Venier, Juana Díez   +7 more
doaj   +1 more source

Reprogramming of m⁶A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia

, 2020
Hypoxia causes a series of responses supporting cells to survive in harsh environments. Substantial post-transcriptional and translational regulation during hypoxia has been observed. However, detailed regulatory mechanism in response to hypoxia is still
Yan-Jie Wang (793358), Ya-Qing Li (5654290), Yao-Ting Li (9283806), Jun-Fang Shi (9283794), Yue Pan (267516), H. Phillip Koeffler (8997653), Yin Zhang (303947), Kai-Shun Hu (9283800), Jian-You Liao (248971), Zhi-Zhi Yang (9283803), Qiao Lai (9283791), Bing Yang (142278), Jing-Wen Peng (7443749), Dong Yin (142456), Jiang-Yun Peng (9283797)   +14 more
core   +1 more source

The role and mechanism of NAT10‐mediated ac4C modification in tumor development and progression

MedComm
RNA modification has emerged as a crucial area of research in epigenetics, significantly influencing tumor biology by regulating RNA metabolism. N‐acetyltransferase 10 (NAT10)‐mediated N4‐acetylcytidine (ac4C) modification, the sole known acetylation in ...
Zhuoran Gu, Libin Zou, Xinjian Pan, Yang Yu, Yongqiang Liu, Zhijin Zhang, Ji Liu, Shiyu Mao, Junfeng Zhang, Changcheng Guo, Wei Li, Jiang Geng, Wentao Zhang, Xudong Yao, Bing Shen   +14 more
doaj   +1 more source