Results 61 to 70 of about 14,898 (228)

Eplerenone inhibits aldosterone-induced CRP generation in rat vascular smooth muscle cells by regulating the MR-ROS-ERK1/2 signal pathway

European Journal of Inflammation, 2017
Atherosclerosis is a chronic inflammatory disease in the vessel wall. As a representative inflammatory cytokine, C-reactive protein (CRP) participates in the formation and development of atherosclerosis.
Xiaolu Zhang, Juntian Liu, Xiaoming Pang, Jingjing Zhao, Shouzhu Xu, Jing Zhao   +5 more
doaj   +1 more source

The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PDF]

, 2015
We assessed the predictive ability of selected biomarkers using N-terminal pro-brain natriuretic peptide (NT-proBNP) as the benchmark and tried to establish a multi-biomarker approach to heart failure (HF) in hypertensive patients. In 120 hypertensive
Agata Bielecka-Dabrowa, Anna Gluba-Brzózka, Campeau, Jacek Rysz, Li, Maciej Banach, Marta Michalska-Kasiczak, Małgorzata Misztal, McCullough, Ravassa, Wei   +10 more
core   +2 more sources

A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers [PDF]

, 2023
Remco de Brouwer, Wouter P. te Rijdt, Edgar T. Hoorntje, Ahmad S. Amin, Folkert W. Asselbergs, Moniek G.P.J. Cox, Jeroen F. van der Heijden, Hans L. Hillege, Jacco C. Karper, Belend Mahmoud, Peter van der Meer, Anton Oomen, Anneline S.J.M. te Riele, Herman H.W. Silljé, Hanno L. Tan, Jan Peter van Tintelen, Dirk J. van Veldhuisen, B. Daan Westenbrink, Ans C.P. Wiesfeld, Tineke P. Willems, Paul A. van der Zwaag, Arthur A.M. Wilde, Rudolf A. de Boer, Maarten P. van den Berg   +23 more
openalex   +1 more source

Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm [PDF]

, 2016
Many conditions culminate in heart failure (HF), a multi-organ systemic syndrome with an intrinsically poor prognosis. Pharmacotherapeutic agents that correct neurohormonal dysregulation and haemodynamic instability have occupied the forefront of ...
Abozguia, AIRE Study Group, Alexander, Alexander, Alexander, Alexander, Ashrafian, Bailey, Bailey, Basu, Beadle, Braunwald, Brown, Burgoyne, Chaitman, Chatterjee, Chung, CIBIS-II Study Group, Cleland, Clerc, Cohn, Cohn, Cohn, CONSENSUS Trial Study Group, Conway, Cook, Dai, Digitalis Investigation Group, Doenst, Dzau, Dzau, Faris, Flather, Follath, Foster, Fox, Fox, Fragasso, Furberg, Gheorghiade, Gladwin, Goffart, Granger, Greenberg, Guazzi, Guazzi, Heymans, Hobbs, Holubarsch, Horowitz, Horowitz, Kantor, Kapil, Kato, Kennedy, Kennedy, Kostis, Larsen, Lee, Lopaschuk, Luiken, Lundberg, Maher, Maier, Mancini, Mann, Mann, Massie, Mccormack, Mcdowell, Mcmurray, Mcmurray, Merit-Hf Study Group, Munzel, Munzel, Neglia, Neubauer, Ormerod, Packer, Packer, Paul, Pawson, Pfeffer, Pfeffer, Pitt, Pitt, Rathore, Rauchhaus, Redfield, Rona, Sack, Sarraf, Schmidt-Schweda, Schrauwen, Schwarz, Shah, Shah, Siddiqi, Singh, SOLVD Investigators, Stanley, Swedberg, Szwed, Taylor, Teerlink, Tilemann, Torre-Amione, Totzeck, Turcani, Unger, Van Der Vusse, Van Faassen, Vardeny, Webb, Yin, Yusuf, Zamani, Zannad, Zannad, Zhang   +119 more
core   +1 more source

Hypokalemic rhabdomyolysis: a rare manifestation of primary aldosteronism [PDF]

, 2015
Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well-known manifestation of hypokalemia. Primary aldosteronism is characterized by hypertension, suppressed plasma renin activity, increased aldosterone excretion and ...
CONCISTRE, ANTONIO, FIACCO, FEDERICA, LETIZIA, Claudio, MARINELLI, CRISTIANO, MITTERHOFER, Anna Paola, PETRAMALA, LUIGI, TINTI, FRANCESCA, UMBRO, ILARIA, ZAVATTO, ASSUNTA, ZINGARETTI, VIVIANA   +9 more
core  

Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes [PDF]

, 2013
Cardiac steatosis and apoptosis are key processes in diabetic cardiomyopathy, but the underlying mechanisms have not been elucidated, leading to a lack of effective therapy.
Ares-Carrasco, Sara, Barbas, Coral, Caro-Vadillo, Alicia, Egido de los Ríos, Jesús, Ferrarini, Alessia, Klett-Mingo, Mercedes, Lorenzo, Óscar, Picatoste, Belén, Ramírez, Elisa, Rupérez, Francisco Javier, Tuñón, José Luis Morales   +10 more
core   +3 more sources

Type of atrial fibrillation and clinical outcomes in patients with heart failure and reduced ejection fraction [PDF]

, 2017
Background: Atrial fibrillation (AF) is common in heart failure (HF), but the outcome by type of AF is largely unknown. Objectives: This study investigated outcomes related to type of AF (paroxysmal, persistent or permanent, or new onset) in 2 ...
Abraham, William T., Desai, Akshay S., Dickstein, Kenneth, Jhund, Pardeep S., Køber, Lars, McMurray, John J.V., Mogensen, Ulrik M., Packer, Milton, Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Zile, Michael R.   +11 more
core   +3 more sources

Stabilization of Early Duchenne Cardiomyopathy With Aldosterone Inhibition: Results of the Multicenter AIDMD Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Duchenne muscular dystrophy incurs nearly universal dilated cardiomyopathy by the third decade of life, preceded by myocardial damage and impaired left ventricular strain by cardiac magnetic resonance.
Subha V. Raman, Kan N. Hor, Wojciech Mazur, Andrea Cardona, Xin He, Nancy Halnon, Larry Markham, Jonathan H. Soslow, Michael D. Puchalski, Scott R. Auerbach, Uyen Truong, Suzanne Smart, Beth McCarthy, Ibrahim M. Saeed, Jeffrey M. Statland, John T. Kissel, Linda H. Cripe   +16 more
doaj   +1 more source

Treatment of Heart Failure with Preserved Ejection Fraction [PDF]

, 2011
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90240/1/phco.31.3.312 ...
Barnes, Megan M., Bleske, Barry E., Dorsch, Michael P., Hummel, Scott L., Koelling, Todd M.   +4 more
core   +1 more source

Endothelial Dysfunction in Human Essential Hypertension [PDF]

, 2016
Although the endothelium has a number of important functions, the term endothelial dysfunction is commonly used to describe impairment in its vasodilatory capacity.
Akiyama, Alexander, Anderson, Antony, Benjamin, Blanco-Rivero, Brehm, Brundtland, Cardillo, Cardillo, Ceconi, Celermajer, Charakida, Charakida, Cockcroft, Corretti, Corretti, Creager, Dawes, Deanfield, Dell’Omo, Deng, Dorresteijn, Dzau, d’Uscio, Erdos, Ergul, Fargin, Farquharson, Fischer, Flammer, Forstermann, Frielingsdorf, Fujimura, Furchgott, Gao, Garnier, Gaziano, Ghiadoni, Ghiadoni, Ghiadoni, Gokce, Gryglewski, Halcox, Hamburg, Haynes, Higashi, Hirooka, Hornig, Imai, Joannides, Juonala, Karthikeyan, Kerth, Kielstein, Kiowski, Klingbeil, Kobayashi, Koh, Kohno, Korkmaz, Krum, Kuvin, Lawes, Linder, Ludmer, Luscher, Luscher, Lyons, Mancia, Mancini, Millgard, Millgard, Modena, Morimoto, Muiesan, Muiesan, Murad, Nakamura, Nitenberg, Panza, Panza, Panza, Park, Pasini, Peller, Perticone, Perticone, Reriani, Rizzoni, Rizzoni, Romero, Rossi, Rossi, Roustit, Roustit, Rubanyi, Rubanyi, Russell, Savoia, Schiffrin, Schiffrin, Schiffrin, Schiffrin, Schiffrin, Schiffrin, Siegrist, Siragy, Suwaidi, Suzuki, Taddei, Taddei, Taddei, Taddei, Taddei, Takiguchi, Tiryaki, Troost, Turner, Tzemos, Tzemos, Ullian, van Hecke, Vanhoutte, Vinereanu, Virdis, Virdis, Vitale, Wagner, Weil, Wilkinson, Wood, Yamanari, Yanagisawa, Yavuz, Yilmaz, Zhang, Zhou   +137 more
core   +3 more sources