Results 11 to 20 of about 44,698 (310)

Emerging EPO and EPO receptor regulators and signal transducers [PDF]

Blood, 2015
AbstractAs essential mediators of red cell production, erythropoietin (EPO) and its cell surface receptor (EPO receptor [EPOR]) have been intensely studied. Early investigations defined basic mechanisms for hypoxia-inducible factor induction of EPO expression, and within erythroid progenitors EPOR engagement of canonical Janus kinase 2/signal ...
David, Kuhrt, Don M, Wojchowski
openaire   +3 more sources

Erythropoietin (EPO) Increases Myelin Gene Expression in CG4 Oligodendrocyte Cells through the Classical EPO Receptor

Molecular Medicine, 2013
Erythropoietin (EPO) has protective effects in neurodegenerative and neuroinflammatory diseases, including in animal models of multiple sclerosis, where EPO decreases disease severity.
Ilaria Cervellini, Alexander Annenkov, Thomas Brenton, Yuti Chernajovsky, Pietro Ghezzi, Manuela Mengozzi   +5 more
doaj   +2 more sources

Impact of Magnesium Oxide Nanoparticles on Erythropoietin Hormone Levels in Sera of Patients with Anemia Accompanied with Diabetic Kidney Disease

Nano Biomedicine and Engineering, 2020
The present research aimed to study the clinical efficacy of novel of impact of magnesium oxide nanoparticles on erythropoietin hormone in blood. Magnesium oxide nanoparticles (MgO NPs) were prepared by the chemical method.
Ameer Radhi Sultan, Fatin Fadhel Mohammed Al-Kazazz, Asma Hadi Mohammed   +2 more
doaj   +1 more source

miR-122 regulates the JAK-STAT signalling pathway by down-regulating EPO in the mammary gland during Streptococcus agalactiae-induced mastitis

Italian Journal of Animal Science, 2020
MicroRNA (miRNA) are single-stranded non-coding RNA of approximately 22 nucleotides estimated to regulate 60% of human and animal genes some of which are associated with cell differentiation, signal transduction and immune processes.
Junhua Pu, Daijie Chen, Shuangfeng Chu, Zhi Chen, Yongliang Fan, Zhipeng Zhang, Juan J. Loor, Yongjiang Mao, Zhangping Yang   +8 more
doaj   +1 more source

Erythropoietin Non-hematopoietic Tissue Response and Regulation of Metabolism During Diet Induced Obesity

Frontiers in Pharmacology, 2021
Erythropoietin (EPO) receptor (EPOR) determines EPO response. High level EPOR on erythroid progenitor cells gives rise to EPO regulated production of red blood cells. Animal models provide evidence for EPO activity in non-hematopoietic tissue mediated by
Soumyadeep Dey, Jeeyoung Lee, Constance T. Noguchi   +2 more
doaj   +1 more source

Effects of Angiotensin II on Erythropoietin Production in the Kidney and Liver

Molecules, 2021
The kidney is a main site of erythropoietin production in the body. We developed a new method for the detection of Epo protein by deglycosylation-coupled Western blotting.
Yukiko Yasuoka, Yuichiro Izumi, Takashi Fukuyama, Hideki Inoue, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Masashi Mukoyama, Yuichi Sato, Jeff M Sands, Katsumasa Kawahara, Hiroshi Nonoguchi   +14 more
doaj   +1 more source

EPO and doping

European Journal of Applied Physiology, 2010
It is with great interest that we read exchanges on intermittent hypoxic (Boning 2009; Ferretti 2009) exposure as a potential doping procedure. Erythropoietin (EPO) does introduce potential concerns in terms of doping, both due to its eVects and side eVects. An earlier publication on exogenous EPO (Noakes 2008) clearly showed an increase of sub-maximal
Balestra, Costantino, Germonpré, Peter
openaire   +4 more sources

The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): Acute renal ischemia may cause acute renal dysfunction due to lack of blood supply; the manifestations are renal tubular cell apoptosis, infiltration of macrophages, and microvascular destruction. Many studies have shown that erythropoietin
Longyan Qin, Xin Lin, Juan Liu, Rong Dong, Jing Yuan, Yan Zha   +5 more
doaj   +1 more source

Design of mine-used integrated data access gateway based on EPON technology

Gong-kuang zidonghua, 2014
On account of many data interfaces of coal mine monitoring and control system and it cannot achieve data unified communication and sharing at present, the paper designed a mine-used integrated data access gateway based on EPON technology combining with ...
GUO Wei, TIAN Hongxia
doaj   +1 more source

Cause and Timing of Death and Subgroup Differential Effects of Erythropoietin in the EPO-TBI Study [PDF]

, 2018
The EPO-TBI study randomized 606 patients with moderate or severe traumatic brain injury (TBI) to be treated with weekly epoetin alfa (EPO) or placebo.
McArthur, Colin, Olivier Huet, Haddad, Samir, Lorraine Little, Durantea, Jacques, Cooper, D. James, Craig French, Markus B. Skrifvars, D. James Cooper, Arabi, Yaseen, Huet, Olivier, French, Craig, Jacques Durantea, Little, Lorraine, Skrifvars, Markus B., Alistair Nichol, Bailey, Michael, Rinaldo Bellomo, Yaseen Arabi, null for the EPO-TBI Investigators and t, Jeffrey Presneill, EPO-TBI Investigators & ANZICS, Colin McArthur, Presneill, Jeffrey, Samir Haddad, Nichol, Alistair, Bellomo, Rinaldo, Michael Bailey   +27 more
core   +1 more source