Results 131 to 140 of about 171,687 (384)

A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012

open access: yesJournal of Research in Medical Sciences, 2013
Background: Carbamazepine has been used as AEDs since 1965, and is most effective against partial seizures. Two basic mechanisms of action have been proposed: 1) enhancement of sodium channel inactivation by reducing high-frequency repetitive firing of ...
Zahra Tolou-Ghamari   +3 more
doaj  

Preparation of an Epoxide Precursor for Palladium-Catalyzed Trimethylenemethane Cycloaddition [PDF]

open access: yes, 2014
In order to produce a highly functionalized five-membered ring useful for further synthetic processes via palladium catalysis, a series of precursors need to be synthesized in order to form the epoxide used in cyclic formation.
Freeland, Chase, Prusinski, William
core   +1 more source

Ligand‐Engineered Metal–Organic Frameworks of 3D Infinite Trinuclear Zinc Units for Photocatalytic Monooxygenation of Sulfenamides

open access: yesAdvanced Science, EarlyView.
The rarely investigated metal–organic frameworks (MOFs) of 3D infinite trinuclear zinc units are designed and synthesized. Through controllable programming of ligands, their Lewis acidity and photoactivity are fine‐tuned to enable these MOFs as promising catalysts for the cycloaddition of CO2 and photocatalytic monooxygenation of sulfenamides and ...
Xinglei He   +8 more
wiley   +1 more source

Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications.

open access: yesJournal of Medicinal Chemistry, 2012
Epoxide hydrolases have been detected in prokaryotes and eukaryotes ranging from plants to mammals.1,2, 3 In mammals these include the soluble epoxide hydrolase (sEH), microsomal epoxide hydrolase (mEH), cholesterol epoxide hydrolase, and leukotriene A4 (
Hong C Shen, B. Hammock
semanticscholar   +1 more source

Innovative Design of PEI‐Modified AMO‐Layered Double Hydroxide for Efficient and Stable Direct Air Capture of CO2

open access: yesAdvanced Science, EarlyView.
An uncalcined, hydroxyl‐rich MgAl layered double hydroxide, synthesized via low‐energy aqueous miscible organic solvent treatment, enables mesopore‐engineered polyethyleneimine anchoring for direct air capture (DAC). The exfoliated structure exposes abundant hydroxyls that stabilize amines via hydrogen bonding, effectively suppressing oxidative ...
Meng Zhao   +6 more
wiley   +1 more source

Selective Chemo‐Divergent Hydrogenation of Ethylene Carbonate Enabled by Multi‐Functional Poly(Ionic Liquids)‐Stabilized Ru Nanoparticles

open access: yesAngewandte Chemie, EarlyView.
A highly efficient and selective chemo‐divergent hydrogenation of cyclic carbonates is promoted by in situ generated poly(ionic liquid)‐stabilized ruthenium nanoparticles (Ru@PIL) catalysts. Under solvent‐free conditions, ethylene carbonate is transformed into either ethylene glycol and CH4 or EtOH and CO2, following a “direct hydrogenation” or a ...
Wenjuan Wang   +2 more
wiley   +2 more sources

New Addition Reactions. III. Addition of Aliphatic Epoxides to Nitriles [PDF]

open access: green, 1962
Ryohei Oda   +3 more
openalex   +1 more source

Engineering graphene by oxidation: a first principles study

open access: yes, 2009
Graphene epoxide, with oxygen atoms lining up on pristine graphene sheets, is investigated theoretically in this Letter. Two distinct phases: metastable clamped and unzipped structures are unveiled in consistence with experiments. In the stable (unzipped)
Kun Xue, Pandey D, Zhiping Xu
core   +1 more source

Home - About - Disclaimer - Privacy