Results 131 to 140 of about 15,949 (256)

Synthesis of enantiopure bis-aziridines, bis-epoxides, and aziridino-epoxides from D-mannitol

, 2006
Apractical synthesis of enantiopure bis-aziridines 11 and 15, bis-epoxides 12 and 17, and aziridino-epoxides 27 and 30 is reported using inexpensive D-mannitol as the starting material.
Sureshkumar, Devarajulu, Maity, Susama, Chandrasekaran, Srinivasan   +2 more
core  

Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry

Bulletin of the Korean Chemical Society, EarlyView.
Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah, Amirreza Mottafegh, Su‐Hyun Yoo, Jongwoon Kim, Minseon Byeon, Juhwan Noh, Yea‐Lee Lee, Jin Suk Myung, Gwang‐Noh Ahn   +8 more
wiley   +1 more source

A Convergent Materials Design Paradigm Across Electro‐ and Photocatalysis for Sustainable Hydrogen Peroxide Production

Carbon Energy, EarlyView.
This review outlines advanced modification strategies for electrocatalytic and photocatalytic H2O2 production, covering bandgap tuning, defect engineering, heterostructure construction, cocatalyst loading, and functional framework design. Structure‐performance correlations are revealed across catalysts such as metal oxides, sulfides, carbon nitrides ...
Na Li, Jie Zhou, Yazhou Zhou, Zhen Yang, Yufeng Wang, Bo Weng, Jinyang Chen, Mingchao Shao, Minfeng Zeng, Wei Zong   +9 more
wiley   +1 more source

Expanding the Scope of Indium in Frustrated Lewis Pair Chemistry

Chemistry – A European Journal, EarlyView.
All good things come in threes: The pyridine‐“protected” FLP tBu2InCH2PtBu2·Py shows three different kinds of reactivity: Besides “typical” FLP activity, it prefers formation of the “soft” isomers for substrates with multiple sites for FLP attack, but reacts with SO2 as a “masked” In/C FLP by insertion into the In─C bond.
Daniel N. Heuer, Jan‐Hendrik Lamm, Beate Neumann, Andreas Mix, Yury V. Vishnevskiy, Norbert W. Mitzel   +5 more
wiley   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

Chemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens, Mark Lambers, Romano V. A. Orru, Jordy M. Saya   +3 more
wiley   +1 more source

Getting the Big Ones to Pack: Crystal Structure of Vitamin K2 With a Chaperone

Chemistry – A European Journal, EarlyView.
A method for obtaining co‐crystals of medium‐size organic molecules and ‐tetrakis(2‐fluoro‐4‐methoxyphenyl)adamantane (TFM) as chaperone was developed. This method yielded a high‐resolution x‐ray crystal structure of menaquinone MK‐4 (vitamin K2), in which layers of chaperone and vitamin guest molecules are found.
Jan Hartenfels, Greta Lília Runge‐Seither, Tim Berking, Johanna Osterbrink, Carsten Wolf, Clemens Richert   +5 more
wiley   +1 more source

Catalysis Conversion of Carbon Dioxide and Epoxides by Tetrahydroxydiboron To Prepare Cyclic Carbonates

A binary catalytic system comprising tetrahydroxydiboron and tetrabutylammonium iodide (TBAI) was used to catalyze the cycloaddition of carbon dioxide (CO2) with epoxides.
Ning Liu (168279), Fei Chen (13690), Jichang Liu (1263291), Yuhui Luo (834780), Hao Zhang (15339)   +4 more
core   +1 more source

MurNAc‐Based Electrophilic Inhibitors of O‐Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation

Chemistry – A European Journal, EarlyView.
A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley   +1 more source

A lumped modelling framework for the epoxidation of vegetable oils and fatty acid methyl esters

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Epoxidized vegetable oils and fatty acid methyl esters are promising bio‐based alternatives to phthalates for plasticizer applications. Their synthesis typically involves the reaction of unsaturated double bonds with peracetic acid in a biphasic liquid–liquid system, where the simultaneous occurrence of reaction and phase partitioning makes ...
Irene Presti, Carlo Pirola, Francesco Megna, Federico Galli   +3 more
wiley   +1 more source

Dispensing of actionable pharmacogenetic drugs among adults receiving cardiovascular disease medications in the Northern Netherlands: A serial cross‐sectional study

Clinical Pharmacology &Therapeutics, EarlyView.
The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang, Guiling Zhou, Jens H. J. Bos, Eelko Hak, Talitha Feenstra, Frank Klont   +5 more
wiley   +1 more source