Results 181 to 190 of about 947,323 (274)

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Single-cell and isoform-specific translational profiling of the mouse brain. [PDF]

Nature
Sison SL, Zampa F, Kofman ER, Choi SY, Jagannatha P, Nguyen GG, Naritomi JT, Shin A, Khorgade A, Jin W, Chen CY, Sievert DM, Mukhopadhyay S, Mizrahi O, Blue SM, Marina RJ, Yang D, Wang CC, Pang Z, Brannan KW, Ye L, Al'Khafaji AM, Yeo GW, Lippi G.   +23 more
europepmc   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source

APOE4-AGE axis is linked to mtDNA release and cGAS-STING-mediated neuroinflammation in the aging brain. [PDF]

Free Radic Biol Med
Akhter F, Akhter A, Zhou J, Xi M, Zhu D.
europepmc   +1 more source

An EPR method for estimating activity of antioxidants in mouse skin using an anthralin-derived radical model

An EPR method for estimating activity of antioxidants in mouse skin using an anthralin-derived radical model
Inhibitory effects of intravenously or orally administered antioxidants on the anthralin-derived radical generated in skin (mainly in the epidermis) of living mice by ultraviolet-A (UVA) irradiation were estimated. Anthralin was applied to the dorsal skin of living mice and the mice were then exposed to UVA.
openaire   +1 more source

Self‐Assembly of Therapeutic Peptides for Enhanced Cancer Therapy: Strategies, Therapeutic Performance, and Future Perspectives

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Therapeutic peptide self‐assembly is governed by multiple non‐covalent interactions, enabling the construction of diverse supramolecular structures. These self‐assembled systems can be engineered through spontaneous self‐assembly of monomers, co‐assembly, or stimulus‐responsive strategies to improve tumor delivery efficiency.
Yuelin Fang, Xue Wan, Shihe Wang, Honglan Dai, Huiling Zeng, Nan Chen, Xinxin Zhang   +6 more
wiley   +1 more source

Cubosome integrated with polymeric carbon nitride and cisplatin: in vivo biodistribution and in vitro photodynamic therapy studies. [PDF]

Discov Nano
Abbas SJ, Mehmood S, Li YH, Yesmin S, Su CK, Sepay N, Chiang CS, Chang WC, Hung YC, Ma WL.   +9 more
europepmc   +1 more source

Nitride MXenes Beyond Carbides: Bridging the Gap Between Computational Prediction and Experimental Realization

Advanced Functional Materials, Volume 36, Issue 89, 5 November 2026.
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley   +1 more source

Mitochondrial oxidative stress promotes the accumulation of advanced glycation end products. [PDF]

PLoS One
Akhter F, Samanta S, Sosunov AA, Wu H, Tieu EK, Yan SF, Yan SS.   +6 more
europepmc   +1 more source

Structure and dynamics of photoexcited chromophore-radical systems: a light-induced EPR investigation

reservedPulsed Dipolar Electron Paramagnetic Resonance (EPR) techniques are powerful tools for obtaining structural information in macromolecules and biological systems labeled with paramagnetic probes, most commonly stable nitroxide radicals.
APPIANI, LORENZO
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