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Reduction of Postprostatectomy Bleeding by Epsilon-Aminocaproic Acid

New England Journal of Medicine, 1962
EPSILON-aminocaproic acid (EACA) is a potent inhibitor of plasminogen activation in relatively low concentrations (5 × 10–4M) and of plasmin at considerably higher concentrations (1 × 10–2M).1 , 2 This drug, first described by Japanese investigators, has the structural formula: Clinical studies have indicated that it is effective in hemorrhagic ...
Perry B Hudson, P B Hudson
exaly   +3 more sources

Epsilon-Aminocaproic Acid in Treatment of Acute Pancreatitis

Scandinavian Journal of Gastroenterology, 1971
During the years 1964-1966, 47 patients with acute pancreatitis were treated with epsilon-aminocaproic acid. All the patients recovered. Another group, consisting of 41 patients, was during the same period treated with Trasylol. Two of these patients died. One had massive pulmonary embolism and pancreatic necrosis. The other had pancreatic necrosis and
exaly   +3 more sources

EPSILON-AMINOCAPROIC ACID IN HÆMATURIA

Lancet, The, 1975
Davidt Purtilo, D T Purtilo
exaly   +2 more sources

Epsilon-Aminocaproic Acid (EACA)

Seminars in Thrombosis and Hemostasis, 2008
Epsilon-aminocaproic acid (EACA) is a synthetic inhibitor of the plasmin-plasminogen system. It is the only potent antifibrinolytic agent which is commercially available in the United States. Effective blood levels of the drug are readily obtainable with either oral or intravenous administration, with very high levels of the drug being found in the ...
J D, Griffin, L, Ellman
openaire   +2 more sources

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