Results 91 to 100 of about 1,675 (190)

Repurposing tranexamic acid as an anticancer drug: a systematic review and meta-analysis

open access: yesJournal of Cancer Research and Clinical Oncology
Purpose Drug repurposing may be an efficient strategy for identifying new cancer treatments. Tranexamic acid (TXA), an antifibrinolytic agent that affects the plasminogen-plasmin pathway, may have potential anticancer effects by influencing tumor cell ...
Karoline Assifuah Kristjansen   +3 more
doaj   +1 more source

A randomized controlled pilot study of epsilon-aminocaproic acid as a topical hemostatic agent for postoperative bleeding in the sheep model of chronic sinusitis

open access: yes, 2008
BackgroundSignificant bleeding with blood clot formation in the postoperative period may predispose to the formation of postoperative adhesions. A topical hemostatic agent would potentially improve postoperative comfort and lessen adhesion formation ...
Thomas, D., Wormald, P.
core   +1 more source

Postoperative bleeding after coronary revascularization. Comparison between tranexamic acid and epsilon-aminocaproic acid.

open access: yes, 2000
BACKGROUND: Microvascular bleeding after Cardiopulmonary bypass (CPB) is mainly due to consumption of clotting factors, platelets damage, and hyperfibrinolysis.
CROSTA A   +8 more
core  

The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial.

open access: yes, 2014
BACKGROUND: Antifibrinolytics can reduce intraoperative blood loss. The primary aim of this study was to determine the efficacy of intraoperative tranexamic acid, epsilon-aminocaproic acid, and placebo at reducing perioperative blood loss and the ...
Lonner, Baron S   +8 more
core   +1 more source

The Role Of Antifibrinolytic Agents In Gynecologic Cancer Surgery

open access: yes, 2006
Objective: To compare the effects of crystalloid and colloid solutions, tranexamic acid and epsilon-aminocaproic acid on the need for allogenic blood transfusion and on coagulation and fibrinolysis parameters.
Canbay, Zgur   +5 more
core   +1 more source

Manejo de la enfermedad de von Willebrand en ginecología y obstetricia: Revisión cualitativa de la literatura A qualitative review of the literature regarding managing Von willebrand disease in obstetrics and gynaecology

open access: yesRevista Colombiana de Obstetricia y Ginecología, 2010
Introducción: la enfermedad de Von Willebrand es el trastorno de la coagulación con mayor prevalencia de mujeres en edad fértil y, por lo tanto, es el trastorno genético de la hemostasia más frecuente en la práctica ginecológica y obstétrica.
Franklin J Espitia-De La Hoz
doaj  

A New Insight on the Radioprotective Potential of Epsilon-Aminocaproic Acid

open access: yes
The aim of the study was to scrutinize the ability of epsilon-aminocaproic acid (EACA) to prevent radiation-induced damage to human cells. Materials and Methods: Human peripheral blood mononuclear cells (PBMCs) were exposed to ionizing radiation at three
Timur Saliyev et al., Dmitriy Beznosko
core  

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