Results 71 to 80 of about 1,675 (190)

Efficacy and Safety of Antifibrinolytic Agents in Reducing Perioperative Blood Loss and Transfusion Requirements in Scoliosis Surgery: A Systematic Review and Meta-Analysis.

PLoS ONE, 2015
BackgroundRoutine use of antifibrinolytic agents in spine surgery is still an issue of debate.ObjectiveTo gather scientific evidence for the efficacy and safety of antifibrinolytic agents including aprotinin, tranexamic acid (TXA) and epsilon ...
Meng Wang, Xin-Feng Zheng, Lei-Sheng Jiang   +2 more
doaj   +1 more source

Enterococcus faecalis Translocation in Sepsis: Fibrinolysis and Mitochondrial Dysfunction Drive Lung Injury

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Sepsis frequently progresses to acute lung injury (ALI), characterised by inflammation, extracellular matrix degradation, and mitochondrial dysfunction. This study identifies Enterococcus faecalis as a gut‐derived bacterium that exploits the host fibrinolytic system for pulmonary translocation, resulting in mitochondrial damage and ...
Chenfei Wang, Dan Lv, Yuan Gao, Xinhui Xu, Changqing Zhu, Song Zhang, Keji Zhang   +6 more
wiley   +1 more source

Comparison of Intraoperative Tranexamic Acid and Epsilon-aminocaproic Acid in Cardiopulminary Bypass Patients: A Natural Experiment

, 2019
Looking at the agents in heart surgery to prevent bleeding. The removal of one of the regular drugs from the market (Aprotinin) provided for a natural experiment to compare the results when Tranexamic Acid or Epsilon-aminocaproic acid are ...
Robich, Mike
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Interaction of a recombinant form of apolipoprotein[a] with human fibroblasts and with the human hepatoma cell line HepG2

Journal of Lipid Research, 1996
We have studied the binding, uptake, and degradation of a recombinant form of apolipoprotein[a] (r-apo[a]) using a cultured cell model. In HepG2 cells and in human fibroblasts, r-apo[a] complexed with low density lipoprotein(LDL) is bound and ...
S P Tam, X Zhang, M L Koschinsky
doaj   +1 more source

The Optimal Dose, Efficacy and Safety of Tranexamic Acid on Hemorrhage Control for High Tibial Osteotomy: A Network Meta‐Analysis

Orthopaedic Surgery, Volume 17, Issue 10, Page 2784-2808, October 2025.
Effect of TXA doses on outcomes for HTO patients. ABSTRACT Objective This systematic review and network meta‐analysis was performed to explore the optimal dose, efficacy, and safety of tranexamic acid (TXA) treatments versus placebo for high tibial osteotomy (HTO) patients.
Zhihu Zhao, Fei Xing, Wei Luo, Xin‐long Ma   +3 more
wiley   +1 more source

Improved purification of the membrane-bound hydrogenase-sulfur-reductase complex from thermophilic archaea using epsilon-aminocaproic acid-containing chromatography buffers.

, 2000
A hydrogenase-sulfur reductase (SR) complex was purified from membrane preparations of the extremely thermophilic, acidophilic archaeon Acidianus ambivalens using a combination of sucrose density gradient centrifugation and column chromatography (FPLC ...
Kletzin, Arnulf, Laska, Simone
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Modular design of synthetic protein mimics. Crystal structure of two seven-residue helical peptide segments linked by .epsilon.-aminocaproic acid

, 1991
Two seven-residue helical segments, Val-Ala-Leu-Aib-Val-Ala-Leu, were linked synthetically with an epsilon-aminocaproic acid (Acp) linker with the intention of making a stable antiparallel helix-helix motif.
Flippen-Anderson, Judith L., Isabella, L, Sukumar, M., Uma, K, Balaram, P., Karle, IL, Balaram, P, Flippen-Anderson, Judith L, Karle, Isabella L., Uma, K., Sukumar, M   +10 more
core   +1 more source

Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]

, 2012
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Martinez-Saguer, I, Wahn, V, V. Wahn, I. Martinez-Saguer, Magerl, Markus, Eberl, W, Meyer-Olson, D, Kurnik, K, P. Staubach-Renz, Staubach-Renz, Petra, Eberl, Wolfgang, Kreuz, Wolfhart, Faßhauer, M, K. Kurnik, Magerl, M, D. Meyer-Olson, T. Kühne, W. Aberer, Staubach-Renz, P, Späth, Peter J., Aberer, W, Späth, P, Kreuz, W, Kurnik, Karin, W. Eberl, Wahn, Volker, P. Späth, Aberer, Werner, Meyer-Olson, Dirk, Martinez Saguer, Inmaculada, M. Faßhauer, W. Kreuz, Faßhauer, Maria, M. Magerl, Kühne, T, Kühne, Thomas   +35 more
core   +1 more source

Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management

Hematology, Transfusion and Cell Therapy
The use of strategies to reduce blood loss and transfusions is essential in the treatment of surgical patients, including in complex cardiac surgeries and those that use cardiopulmonary bypass.
Juan Carlos Montano-Pedroso, Fernanda Vieira Perini, Enis Donizetti, Luciana Correa Oliveira, Roseny dos Reis Rodrigues, Silvia Renata Cornélio Parolin Rizzo, Guilherme Rabello, Dante Mario Langhi, Junior   +7 more
doaj   +1 more source

Treatment of hypermenorrhea due to intrauterine contraseptives with epsilon aminocaproic acid

, 1981
Intrauterin kontraseptif araç kullanımına bağlı hipermenoresi olan 23 hastada menstruasyon sırasında oral yoldan Epsilon aminocaproic asitten günde 3 defa 2 gr. uygulanmıştır.

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