Results 161 to 170 of about 396,299 (201)
Some of the next articles are maybe not open access.

A simple method for purification of epsilon toxin of Clostridium perfringens type D for serum neutralization assay.

Journal of Microbiological Methods, 2021
Enterotoxaemia, a disease that affects domestic ruminants, is caused by the epsilon toxin of Clostridium perfringens type D and B. Control and prophylaxis are based on systemic vaccination of small ruminant herds with epsilon toxoid.
L. Khiav, A. Emadi, A. Zahmatkesh
semanticscholar   +1 more source

Distribution of labeled Clostridium perfringens epsilon toxin in mice

Toxicon, 1991
The in vivo distribution of labeled Clostridium perfringens epsilon toxin after i.v. administration to mice was investigated. High amounts of radioactivity were found in the kidneys and the brain, and small amounts were in the heart, lungs, liver and stomach.
M, Nagahama, J, Sakurai
openaire   +2 more sources

Expression and Characterization of Recombinant Epsilon Toxin Variants of Clostridium perfringens Type D in Pichia pastoris.

Protein Expression and Purification
Epsilon toxin (ETX) is the most potent clostridial toxin after tetanus and botulinum neurotoxins. ETX belongs to the heptameric β-pore-forming proteins produced by Clostridium perfringens types B and D, which cause fatal enterotoxemia and significant ...
M. Manfredi   +3 more
semanticscholar   +1 more source

Clostridium perfringens Epsilon Toxin: Structural and Mechanistic Insights

2016
Epsilon toxin (ETX) is produced by strains of Clostridium perfringens classified as type B or D. ETX belongs to the heptameric β-pore-forming toxins including Aeromonas aerolysin and Clostridium septicum alpha toxin, which are characterized by the formation of a pore through the plasma membrane of eukaryotic cells and containing a β-barrel composed of ...
Popoff, Michel R.   +2 more
openaire   +2 more sources

ANTIBODY RESPONSE TO EPSILON TOXIN OF CLOSTRIDIUM PERFRINGENS IN CAPTIVE ADULT SPRINGBOK (ANTIDORCAS MARSUPIALIS), IMPALA (AEPYCEROS MELAMPUS), ALPACA (VICUGNA PACOS), AND RED-NECKED WALLABY (MACROPUS RUFOGRISEUS) OVER A YEAR

Journal of zoo and wildlife medicine, 2021
: Enterotoxemia is an important issue in various zoological taxa. In this study, serologic responses over a 1-yr period after vaccination with a multivalent clostridial vaccine were evaluated in 10 adult springboks (Antidorcas marsupialis), 12 impalas ...
Estelle Rousselet   +7 more
semanticscholar   +1 more source

Investigation of genetic toxicity and oxidative stress of Clostridium perfringens epsilon toxin type D on human peripheral blood lymphocytes.

Microbial Pathogenesis, 2021
Epsilon toxin (Etx) is an enormously potent pore-forming toxin and a category B biological agent. Etx is the main virulence determinant of Clostridiumperfringens types B and D toxin. It has a cytotoxic effect on distal and collecting kidney tubules. Also,
M. Shokrzadeh   +4 more
semanticscholar   +1 more source

Clostridium perfringens Epsilon Toxin Mutant I51C as a Recombinant Vaccine Candidate Against Enterotoxemia.

Clinical Laboratory
BACKGROUND Clostridium perfringens type B and D strains produce epsilon toxin (ETX), which can lead to enterotoxemia, an extremely lethal disease that has significant consequences for the farming of domestic ruminants, specifically sheep and goats.
Elmira Nakhaipour   +3 more
semanticscholar   +1 more source

Vaccines against the category B toxins: Staphylococcal enterotoxin B, epsilon toxin and ricin

Advanced Drug Delivery Reviews, 2005
The threat of bioterrorism worldwide has accelerated the demand for the development of therapies and vaccines against the Category B toxins: staphylococcal enterotoxin B (SEB), epsilon toxin (ETX) produced by Clostridium perfringens types B and D, and ricin, a natural product of the castor bean.
openaire   +2 more sources

Molecular basis of toxicity ofClostridium perfringensepsilon toxin

The FEBS Journal, 2011
Clostridium perfringensε‐toxin is produced by toxinotypes B and D strains. The toxin is the aetiological agent of dysentery in newborn lambs but is also associated with enteritis and enterotoxaemia in goats, calves and foals. It is considered to be a potential biowarfare or bioterrorism agent by the US Government Centers for Disease Control and ...
Monika, Bokori-Brown   +5 more
openaire   +2 more sources

Naturally acquired antibodies against Clostridium perfringens epsilon toxin in goats

Veterinary Immunology and Immunopathology, 2008
Clostridium perfringens type D-producing epsilon toxin is a common cause of death in sheep and goats worldwide. Although anti-epsilon toxin serum antibodies have been detected in healthy non-vaccinated sheep, the information regarding naturally acquired antibodies in ruminants is scanty.
Veschi, Josir Laine A.   +4 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy