Results 141 to 150 of about 1,167,902 (208)
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Identification and Functional Analysis of Epstein-Barr Nuclear Antigen 2 (EBNA2) Target Genes [PDF]
, 2004 Santak, Maja
core +1 more source
Human Cortical Neural Progenitor Cells
Cell Proliferation, EarlyView.
An‐Xin Wang +29 more
wiley +1 more source
Viruses, Periodontitis, and Systemic Diseases
Journal of Periodontal Research, EarlyView.This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
Journal of Periodontal Research, EarlyView.This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective To evaluate whether the age at diagnosis of oral squamous cell carcinoma (OSCC) has changed over time and to assess whether stage at presentation has varied across decades. Methods A systematic review was conducted according to PRISMA guidelines (PROSPERO registration: CRD420251048070).
Francesco Scilla +10 more
wiley +1 more source
Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia
Oral Diseases, EarlyView.ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio +8 more
wiley +1 more source
Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules
Plant Biotechnology Journal, EarlyView.ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan +8 more
wiley +1 more source
Epstein-Barr virus and persistent graft dysfunction after liver transplantation
, 1991 Epstein-Barr virus infection has been associated with a broad spectrum of clinical manifestations, depending on the immune status of the host. In this report, we describe two liver transplant patients who received hepatic allografts from donors ...
Smith, T. F. +5 more
core
Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chen Wang +11 more
wiley +1 more source