Results 171 to 180 of about 1,167,902 (208)

Analysis of the Role of N‐Linked Glycans on Human CD1d Molecules

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT CD1d is a cell‐surface expressed glycoprotein that presents a variety of lipid and glycolipid antigens to invariant natural killer T‐cells (iNKT). We have examined the role of the N‐linked glycans on the human CD1d (hCD1d) in modulating the responses of iNKT cells using a combination of cell‐free, cell‐based assays and in silico analyses ...
Syamdas Bandyopadhyay, Sayantan Pradhan
wiley   +1 more source

Rapid‐Onset Amoxicillin–Clavulanate Liver Injury Requires Stronger Exclusion of Alternative Causes and Fuller Causality Reporting in Atypical DILI Case Reports

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Rapid‐onset drug‐induced liver injury after amoxicillin–clavulanate is clinically important, but atypical latency requires particularly careful exclusion of alternative causes. Future reports should provide complete exposure chronology, infectious and autoimmune exclusion, concomitant‐drug assessment, RUCAM itemization, and longer biochemical ...
Muhammad Abdullah Awan, Hammad‐ud‐din Raza   +1 more
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Dimethyl Fumarate‐Associated Acute Hepatocellular Injury Assessed for Causality Using the Updated RUCAM: A Biopsy‐Supported Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Dimethyl fumarate may rarely cause severe hepatocellular injury. In a 26‐year‐old woman, liver enzymes rose soon after treatment initiation, and biopsy supported DILI. Updated RUCAM assessment yielded 6, indicating probable causality, supported by dechallenge.
Ophir Lavon, Maram Salameh
wiley   +1 more source

Delayed Recognition of Hemophagocytic Lymphohistiocytosis in a Child With Refractory Fever: A Case From Pakistan

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening, exceedingly rare hyperinflammatory syndrome that typically presents with nonspecific symptoms such as fever and cytopenia. An early diagnosis of HLH is a significant clinical challenge, especially in children with presentations mimicking common infectious diseases.
Muhammad Taaha Siddiqui, Nawal Fatima, Khola Qazi, Karan Chaman Lal, Md. Faisal Ahmed   +4 more
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Oral Relapsing Lymphomatoid Papulosis: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Lymphomatoid papulosis (LyP) is a CD30+ T‐cell lymphoproliferative disorder rarely involving mucosa, where it may mimic aggressive lymphomas. This case highlights its chronic relapsing course, diagnostic challenges with ALK‐negative anaplastic T‐cell lymphoma, and the importance of long‐term follow‐up despite a favorable prognosis.
A. Bitton, P. Le Gatt, S. Barete, L. Eck, P. Reimbold, G. Lescaille, N. Gauthier, J. Rochefort   +7 more
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Targeting the GPR183/EBI2‒oxysterol axis in tuberculosis: Immunometabolic regulation and prospects for host‐directed therapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
GPR183/EBI2 links oxysterol metabolism with immune‐cell positioning and macrophage function in tuberculosis. The 7α,25‐OHC‐GPR183 axis regulates macrophage trafficking, autophagy and type I interferon responses. GPR183 represents a potential immunometabolic target for host‐directed therapy against tuberculosis..
Junfei Wang, Yingnan Zhou, Xunming Ji, Haiping Zhao, Lingjun Zhan   +4 more
wiley   +1 more source

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

Head &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan, Avraham Eisbruch, June Corry, Sandra Nuyts, Pim de Graaf, Luiz P. Kowalski, Jonathan J. Beitler, Sweet Ping Ng, William M. Mendenhall, M. P. Sreeram, Karthik N. Rao, Anna Luíza Damaceno Araújo, Alfio Ferlito   +12 more
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Cytokine‐Driven Hyperinflammation in Long COVID: Mechanisms, Biomarkers, Complement Dysregulation, and Emerging Immunotherapies—A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
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Colorectal Cancer and Intestinal Protozoan Infections: Prevalence, Risk Factors, and Molecular Confirmation in Western Iran: A Descriptive Case‐Control Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Infections are recognized contributors to cancer development. This study aimed to assess the prevalence, socio‐demographic characteristics, and risk factors associated with intestinal protozoan parasites in patients with colorectal cancer (CRC) in Western Iran.
Alireza Moayyedkazemi, Amal Khudair Khalaf, Sima Nik Khah Behnamiri, Asghar Sepahvand, Neda Niazi, Maryam Sepahvand, Hossein Mahmoudvand   +6 more
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Burden and Correlates of Multiple Chronic Infections and Their Associations With Cancer Incidence in Chinese Adults: A Large Case‐Cohort Study

International Journal of Cancer, Volume 159, Issue 5, Page 1282-1295, 1 September 2026.
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang, Jonathan Clarke, Lea Kröller, Christiana Kartsonaki, Hannah Fry, Rima Jeske, Andrew Gordon, Sarah Clark, Michael Hill, Daniel Avery, Yiping Chen, Huaidong Du, Jun Lv, Dianjianyi Sun, Canqing Yu, Liming Li, Iona Y. Millwood, Tim Waterboer, Zhengming Chen, on behalf of the China Kadoorie Biobank Collaborative Group, Junshi Chen, Zhengming Chen, Robert Clarke, Rory Collins, Liming Li, Jun Lv, Richard Peto, Robin Walters, Liming Li, Jun Lv, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Yuting Han, Can Hou, Qingmei Xia, Chao Liu, Pei Pei, Lang Pan, Xiao Han, Honglu Bian, Xinxin Chen, Daniel Avery, Maxim Barnard, Derrick Bennett, Ruth Boxall, Yiping Chen, Zhengming Chen, Jonathan Clarke, Robert Clarke, Huaidong Du, Ahmed Edris Mohamed, Hannah Fry, Prapthi Harish, Pek Kei Im, Andri Iona, Christiana Kartsonaki, Kshitij Kolhe, Hubert Lam, Kuang Lin, James Liu, Iona Millwood, Sam Morris, Qunhua Nie, Alfred Pozarickij, Maryam Rahmati, Paul Ryder, Maruf Sarder, Dan Schmidt, Becky Stevens, Iain Turnbull, Robin Walters, Baihan Wang, Lin Wang, Neil Wright, Ling Yang, Xiaoming Yang, Pang Yao, Zengchang Pang, Ruqin Gao, Kunzheng Lv, Shanpeng Li, Haiping Duan, Shaojie Wang, Yongmei Liu, Ranran Du, Liang Cheng, Xiaocao Tian, Hua Zhang, Dan Hu, Xiaoyan Zheng, Yujie Wang, Wei Sun, Shichun Yan, Chi Wang, Zhenyuan Wu, Lishun Zhai, Zhaoxi Pang, Shiwen Dong, Li Liu, Dapeng Yin, Bin He, Ying Liu, Xingren Wang, Tingting Ou, Xiangyang Zheng, Dewei Zheng, Shuai Yang, Lihui Li, Xingjiao Chen, Yan Xu, Jinyi Zhou, Ran Tao, Jian Su, Xikang Fan, Xuejia Chen, Yuxiao Huang, Yan Lu, Yujie Hua, Li Xing, Shuxian Wang, Jianrong Jin, Juping Ma, Jinchao Liu, Kaifei Zhu, Hongfu Ren, Xingfeng Shen, Ge Zhong, Wei Mao, Zhenzhen Lu, Yanxu Zhong, Lifang Zhou, Rong Pan, Jian Lan, Xiaoping Tan, Jinxue Tan, Yishan Xie, Liuping Wei, Liyuan Zhou, Sisi Wang, Xianping Wu, Ningmei Zhang, Xiaofang Chen, Xiaoyu Chang, Zhuo Wang, Yujin He, Mingqiang Yuan, Ling Wang, Xiaofang Chen, Zhaodong Wang, Qiang Sun, Yang Lin, Faqing Chen, Xiaolan Ren, Lijun Chang, Feiming Zhong, Jianjun Feng, Weijie Hu, Xiaofang Zhang, Yalin Chen, Honghong Wang, Jun Wang, Linqi Diao, Zhiwei Han, Dengjun Zhu, Kai Kang, Shixian Feng, Wenjie Yang, Huizi Tian, Yali Yan, Bing Han, Li Gao, Shaofang Li, Tianfang Xing, Wei Tang, Xiaolin Li, Huarong Sun, Xiaocong Zhao, Ying Li, Chen Hu, Pan He, Xukui Zhang, Yuanyuan Jin, Lan Luo, Min Yu, Ruying Hu, Hao Wang, Weiwei Gong, Jieming Zhong, Meng Wang, Chunxiao Xu, Keqing Gong, Hao Xu, Yuan Cao, Kaixu Xie, Lingli Chen, Xiaomei Tu, Junlong Pan, Xiaojun Li, Li Yin, Huilin Liu, Yuan Liu, Lei Yin, Xian Xie, Jing Wang, Bo Xiao, Zongwei Deng, Yuan Peng, Libo Zhang, Chan Qu, li Deng, Qili Jiang, Yanling Chen   +212 more
wiley   +1 more source