Results 131 to 140 of about 108,615 (251)

Herpesvirus genome integration in whole‐genome sequences of dementia and control cohorts

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The infectious hypothesis suggests that microbes like herpesviruses may play a role in the pathogenesis of Alzheimer's disease (AD) and other related dementias through methods that may include viral genome integration. The occurrence of herpesvirus genome integration in dementia patients has not been thoroughly characterized ...
Stacey L. Piotrowski   +27 more
wiley   +1 more source

Distinct HLA Associations for Antibody Multireactivity With Citrulline‐Containing Type II Collagen Epitopes Versus More Limited Antibody Reactivity With Citrulline‐Containing IgG Epitopes in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, Volume 78, Issue 3, Page 603-612, March 2026.
Objective Anticitrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among patients with RA, including for motif‐containing epitopes in important self‐antigens like ...
S. Janna Bashar   +4 more
wiley   +1 more source

Elucidating the Causal Relationships Between B Cells, Dendritic Cells, and Multiple Sclerosis Pathogenesis

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
This study presents an integrative pipeline linking immune cell traits to multiple sclerosis (MS) susceptibility. Genome‐wide association and Mendelian randomization analyses revealed causal roles of immune cells in MS risk. Colocalization and pleiotropy mapping identified candidate genes, further refined through functional annotation, network analysis,
Xuefei Wang, Yangwei Wang, Xiaojing Liu
wiley   +1 more source

Smoking, Alcohol, and Their Interaction in the Risk of Head and Neck Cancer: A Nationwide Cohort Study

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Smoking and alcohol drinking are established causes of head and neck cancer (HNC), yet their combined effect and variation by anatomic sub‐site remain incompletely defined. Methods We followed 5,985,244 Korean adults (≥ 30 years) who attended National Health Insurance health screening in 2002–2003 until 31 December 2019.
Eunjung Park   +5 more
wiley   +1 more source

Case Report: A rare case of Epstein-Barr virus mucocutaneous ulcers occurring in the eyeball and literature review. [PDF]

open access: yesFront Med (Lausanne)
Ke X   +9 more
europepmc   +1 more source

A Novel Modified Bu/Vp16/cy/Flu/Ara‐C Conditioning Regimen Enhances Outcomes for High‐Risk Acute Lymphoblastic Leukemia Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Purpose Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) effectively treats high‐risk acute lymphoblastic leukemia (ALL), yet challenges persist due to post‐transplant relapse and conditioning regimen toxicities. The determination of an appropriate preconditioning regimen is critical to improving patient outcomes.
Xiaoyan Zhao   +6 more
wiley   +1 more source

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