Results 191 to 200 of about 1,925,886 (292)

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3257-3264, September 2026.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo   +12 more
wiley   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

open access: yesBiotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen   +2 more
wiley   +1 more source

Endobronchial Epstein-Barr Virus-Associated Smooth Muscle Tumor in Advanced HIV Infection: A Rare Case. [PDF]

open access: yesAm J Case Rep
Wannasai K   +4 more
europepmc   +1 more source

Prognostic Value of Hemoglobin, Albumin, Lymphocyte, and Platelet Score in Locally Advanced Nasopharyngeal Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Objective To investigate the prognostic value of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in patients with locally advanced nasopharyngeal carcinoma (LANPC) receiving concurrent chemoradiotherapy (CCRT), and to clarify its predictive significance for overall survival (OS), progression‐free survival (PFS), locoregional ...
JunMei Song   +6 more
wiley   +1 more source

Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology

open access: yes
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 10, Page e864-e867, October 2026.
Chen Wang   +11 more
wiley   +1 more source

MAGEA Family Gene Expression Influences Survival in Intestinal‐Type Gastric Cancer

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Gastric cancer (GC) is a heterogeneous disease characterized by diverse molecular profiles and distinct histological subtypes, each with differing prognoses and therapeutic responses. Melanoma‐associated antigen‐A (MAGEA) genes encode cancer testis antigens frequently expressed in tumor tissue and in limited amounts in normal tissues, making ...
Silke Neumann   +4 more
wiley   +1 more source

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