Results 41 to 50 of about 73,157 (247)

Cardiovascular involvement in Epstein–Barr virus infection

Frontiers in Immunology, 2023
Cardiovascular involvement is an uncommon but severe complication of Epstein–Barr virus (EBV) infection caused by direct damage and immune injury. Recently, it has drawn increasing attention due to its dismal prognosis. It can manifest in various ways, including coronary artery dilation (CAD), coronary artery aneurysm (CAA), myocarditis, arrhythmias ...
Xinying Chen, Yingying Li, Lijun Deng, Lijun Deng, Lianyu Wang, Wenting Zhong, Junbin Hong, Liyu Chen, Jinghua Yang, Jinghua Yang, Bin Huang, Bin Huang, Xiaolan Xiao, Xiaolan Xiao   +13 more
openaire   +3 more sources

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

A Lupus Hepatitis Case and its Association with Igm Antibodies against Cytomegalovirus, Herpes Simplex and Herpes Zoster Viruses

European Journal of Inflammation, 2009
The hypothesis for a role of viral infections on the pathogenesis of systemic lupus erythematosus has been discussed in many works, particularly that of cytomegalovirus and Epstein Barr virus infections as trigger of autoimmune processes.
A. Riccio MD, G. Morelli, M.G. Sangiolo, R. Morante, C. Esposito, G. Tarantino   +5 more
doaj   +1 more source

Late Onset Epstein Barr Virus Seropositive Posttransplant Lymphoproliferative Disorder in Two Renal Transplant Receivers

Turkish Journal of Hematology, 2013
Posttransplant malignancy is one of the most important complications of organ transplantation. Immunosuppressive drugs, viral infections such as human herpes virus 8 or Epstein-Barr virus, exposure to carcinogenic factors such as sun, and host factors ...
Saime Paydaş, Semra Paydaş, Mustafa Balal, Arbil Açıkalın, Melek Ergin, Emel Gürkan, Fikri Başlamışlı   +6 more
doaj   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Acute ischemic stroke in a young adult in association with Epstein–Barr virus infection: a case report

Journal of Medical Case Reports
Background Ischemic strokes are a leading cause of disability. While traditional risk factors including hypertension and diabetes are common, younger adults may experience strokes from less typical causes, such as infections. This case report presents an
Haya Al-Taweel, Andrew Matta, Logan Moore, Marcus Chacon   +3 more
doaj   +1 more source

The Effectiveness of Complex Use of Inosine Pranobex and Recombinant Interferon-

Детские инфекции (Москва), 2015
The purpose of research — improvement of treatment programs for chronic Epstein-Barr virus mono-infection and mixed with clamidiosis infection in frequently ill children with use of inosine pranobex (isoprinosine) and recombinant interferon-a2b (viferon).
E. N. Simovanyan, V. B. Denisenko, A. V. Grigoryan   +2 more
doaj   +1 more source

Type I interferon drives dysfunction of a distinct CD8+ HLA‐DRB1+ T cell subset in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long, Elio Carmona, Mikhail G Dozmorov, Amr H Sawalha   +3 more
wiley   +1 more source

Destroy, what destroys you

OncoImmunology, 2020
New evidence indicates the importance of CD137 for controlling Epstein-Barr virus (EBV) infections. (1) Mutations in CD137 predispose to EBV-associated diseases. (2) EBV induces ectopic CD137 expression, thereby activating a negative feed-back regulation
Khang Luu, Emily Nickles, Herbert Schwarz   +2 more
doaj   +1 more source

Epstein-Barr virus infection in children with AIDS [PDF]

Jornal de Pediatria, 1998
OBJECTIVE: The association of the HIV and Epstein-Barr virus infections has been reported in several studies, specially in children that present lymphocytic interstitial pneumonitis. The analysis of the incidence of Epstein-Barr virus infection was performed in children with AIDS, in those with AIDS with and without lymphocytic interstitial pneumonitis,
A P, Carvalho, L V, Gandolfi, E, Tonelli
openaire   +2 more sources