Results 51 to 60 of about 73,157 (247)

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo   +12 more
wiley   +1 more source

MIMICKING LYMPHADENOPATHY

open access: yesGomal Journal of Medical Sciences, 2022
Among patients with malignancy affecting organs like uterus, breast, stomach, lungs or lymphomas, Sarcoid-like granulomas can often occur. Some tumours like Hodgkin's and non Hodgkin lymphoma have shown such reactions. In parallel, HL is widely distorted
Arvindh Manohar, Periyasamy Manimekalai
doaj  

Variants of Epstein—Barr viral infection course in infectious mononucleosis nidus for the children

open access: yesБюллетень сибирской медицины, 2003
The aim of this investigation is to assess variants of Epstein—Barr viral infection course in infectious mononucleosis nidus. There have been examined 5 groups of preschool institutions, in each there was found 1 case of typical infectious mononucleosis ...
A. P. Pomogaeva, O. I. Galaktionova
doaj   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

open access: yesBiotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady   +6 more
wiley   +1 more source

Diagnostic Usefulness of Cell Block Samples in Fluid Overload‐Associated Large B‐Cell Lymphoma

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Hiroyuki Okanishi   +14 more
wiley   +1 more source

Prevalence of human herpesvirus 8 infection in systemic lupus erythematosus

open access: yesVirology Journal, 2011
Background For decades, scientists have tried to understand the environmental factors involved in the development of systemic lupus erythematosus (SLE), in which viral infections was included.
Sun Shipeng   +4 more
doaj   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun   +11 more
wiley   +1 more source

Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis

open access: yesCase Reports in Infectious Diseases, 2016
Epstein-Barr virus (EBV) usually causes mild, asymptomatic, and self-limited infections in children and adults; however, it may occasionally lead to severe conditions such as neurological diseases, malignant diseases, hepatic failure, and myocarditis ...
Gulsen Akkoc   +7 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

Processes of Airway Remodeling in Children with Bronchial Asthma on the Background of Intracellular Infections

open access: yesZdorovʹe Rebenka, 2015
This article provides information about the processes of airway remodeling in children with bronchial asthma. There are described the changes in the levels of matrix metalloproteinases, tissue inhibitor of matrix metalloproteinase, transforming growth ...
O.Ye. Chernyshova
doaj   +1 more source

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