Results 91 to 100 of about 2,883,949 (197)

Contributions of the EBNA1 Protein of Epstein-Barr Virus Toward B-Cell Immortalization and Lymphomagenesis

, 2012
Epstein-Barr Virus (EBV) is a human herpesvirus, infecting 95% of humans, that is causally associated with the benign B-cell proliferative disorder, infectious mononucleosis.
Amber T Washington, Ashok A. Aiyar
semanticscholar   +1 more source

Conditional immortalization of human B cells by CD40 ligation [PDF]

, 2008
It is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro.
Mayr, C., Caroline Zentz, Reinhard Zeidler, Hammerschmidt, W., Wolfgang Hammerschmidt, Wiesner, Martina, Wimmer, Rainer, Wiesner, M., Christine Mayr, Hammerschmidt, Wolfgang, Zentz Caroline, Zentz, C., Moosmann, A., Zeidler, Reinhard, Wiesner Martina, Moosmann Andreas, Andreas Moosmann, Mayr Christine, Wimmer, R., Wimmer Rainer, Zentz, Caroline, Hammerschmidt Wolfgang, Mayr, Christine, Martina Wiesner, Moosmann, Andreas, Rainer Wimmer, Zeidler Reinhard, Zeidler, R.   +27 more
core   +1 more source

Tomato chocolàte virus: a new plant virus infecting tomato and a proposed member of the genus Torradovirus [PDF]

, 2010
A new virus was isolated from a tomato plant from Guatemala showing necrotic spots on the bases of the leaves and chocolate-brown patches on the fruits.
Verbeek, M., Dullemans, A.M., Heuvel, J.F.J.M., van den, Paul Maris, van den Heuvel, J.F.J.M., Maris, P.C., Vlugt, R.A.A., van der, Hans van den Heuvel, Martin Verbeek, Annette Dullemans, René van der Vlugt, van der Vlugt, R.A.A.   +11 more
core   +1 more source

A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]

, 2011
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn, Nicole L. Edworthy, Andrew J. Easton, Meng, Bo, Easton, A. J. (Andrew J.), Bo Meng, Scott, P. D. (Paul D.), Marriott, Anthony C., Anthony C. Marriott, Nigel J. Dimmock, Dimmock, N. J., Paul D. Scott   +11 more
core   +1 more source

Vaccinia virus replication is not affected by APOBEC3 family members [PDF]

, 2006
Background: The APOBEC3G protein represents a novel innate defense mechanism against retroviral infection. It facilitates the deamination of the cytosine residues in the single stranded cDNA intermediate during early steps of retroviral infection.
Sutter Gerd, Kremer Melanie, Schnierle Barbara S, Yasemin Suezer, Suezer, Yasemin, Martinez-Fernandez Yolanda, Schnierle, Barbara, Münk Carsten, Sutter, Gerd, Yolanda Martinez-Fernandez, Melanie Kremer, Barbara S Schnierle, Münk, Carsten, Suezer Yasemin, Gerd Sutter, Martinez-Fernandez, Yolanda, Carsten Münk, Kremer, Melanie   +17 more
core   +1 more source

Plasma Epstein-Barr Virus DNA load for diagnostic and prognostic assessment in intestinal Epstein-Barr Virus infection

Frontiers in Cellular and Infection Microbiology
BackgroundThe prospective application of plasma Epstein-Barr virus (EBV) DNA load as a noninvasive measure of intestinal EBV infection remains unexplored.
Chunxiang Ma, Chunxiang Ma, Chunxiang Ma, Mingshan Jiang, Mingshan Jiang, Mingshan Jiang, Jiaxin Li, Jiaxin Li, Jiaxin Li, Zhen Zeng, Zhen Zeng, Zhen Zeng, Yushan Wu, Yushan Wu, Yushan Wu, Rui Cheng, Rui Cheng, Rui Cheng, Hao Lin, Hao Lin, Hao Lin, Jiangmei Pang, Jiangmei Pang, Jiangmei Pang, Fang Yin, Fang Yin, Fang Yin, Yongbin Jia, Yongbin Jia, Yongbin Jia, Lili Li, Lili Li, Lili Li, Hu Zhang, Hu Zhang, Hu Zhang   +35 more
doaj   +1 more source

Epstein-Barr Virus Sequence Variation—Biology and Disease

Pathogens, 2012
Some key questions in Epstein-Barr virus (EBV) biology center on whether naturally occurring sequence differences in the virus affect infection or EBV associated diseases. Understanding the pattern of EBV sequence variation is also important for possible
Stelios Tzellos, Paul J. Farrell
doaj   +1 more source

Inhibitors of the interferon response enhance virus replication in vitro. [PDF]

, 2014
This work was supported by the University of St Andrews (CSA, CES) and the Wellcome Trust (grant 087751/A/08/Z) (RER).Virus replication efficiency is influenced by two conflicting factors, kinetics of the cellular interferon (IFN) response and induction ...
Richard E. Randall, Catherine S. Adamson, Catherine S Adamson, Claire E Stewart, Richard E Randall, Adamson, Catherine S, Stewart, Claire Emma, Randall, Richard Edward, Claire E. Stewart   +8 more
core   +1 more source

A significant sex--but not elective cesarean section--effect on mother-to-child transmission of hepatitis C virus infection

, 2005
BACKGROUND: Risk factors for mother-to-child transmission of hepatitis C virus (HCV) are poorly quantified. METHODS: We conducted a European multicenter prospective study of HCV-infected pregnant women and their infants.
LANARI, MARCELLO, European, Paediatric Hepatitis C. Virus Network   +1 more
core   +1 more source

Potential Cellular Functions of Epstein-Barr Nuclear Antigen 1 (EBNA1) of Epstein-Barr Virus

Viruses, 2013
Epstein-Barr Nuclear Antigen 1 (EBNA1) is a multifunctional protein encoded by EBV. EBNA1’s role in maintaining EBV in latently proliferating cells, by mediating EBV genome synthesis and nonrandom partitioning to daughter cells, as well as ...
Danielle Westhoff Smith, Bill Sugden
doaj   +1 more source