Control of gammaherpesvirus latency by latent antigen-specific CD8(+) T cells [PDF]
The contribution of the latent antigen-specific CD8(+) T cell response to the control of gammaherpesvirus latency is currently obscure. Some latent antigens induce potent T cell responses, but little is known about their induction or the role they play ...
Blackman, M A +7 more
core
Efficacy and safety of tabelecleucel in patients with EpsteinBarr Virus-associated leiomyosarcomas (EBV+ LMS) [PDF]
L.S. Kurlander +16 more
openaire +1 more source
An investigation of the epigenetic and transcriptional changes which follow Epstein-Barr virus infection of germinal centre B cells [PDF]
Although Epstein–Barr virus (EBV) usually establishes a harmless infection in human memory B cells, it is implicated in the development of germinal centre (GC) B-cell-derived malignancies, including Hodgkin’s lymphoma (HL).
Leonard, Sarah Miriam
core
Potential Cellular Functions of Epstein-Barr Nuclear Antigen 1 (EBNA1) of Epstein-Barr Virus
Epstein-Barr Nuclear Antigen 1 (EBNA1) is a multifunctional protein encoded by EBV. EBNA1’s role in maintaining EBV in latently proliferating cells, by mediating EBV genome synthesis and nonrandom partitioning to daughter cells, as well as ...
Danielle Westhoff Smith, Bill Sugden
doaj +1 more source
Unexpected structure of Epstein–Barr virus lytic cycle activator Zta [PDF]
The key viral gene responsible for initiating the replicative cycle of EpsteinBarr virus (EBV), termed BZLF1, encodes the multifunctional protein Zta (ZEBRA or Z).
Alison Sinclair (4460713)
core
Epstein-Barr Virus in Systemic Autoimmune Diseases
Systemic autoimmune diseases (SADs) are a group of connective tissue diseases with diverse, yet overlapping, symptoms and autoantibody development. The etiology behind SADs is not fully elucidated, but a number of genetic and environmental factors are ...
Anette Holck Draborg +2 more
doaj +1 more source
Influenza A viruses and PI3K signalling [PDF]
The influenza A virus non-structural (NS1) protein is multifunctional, and during virus-infection NS1 interacts with several factors in order to manipulate host-cell processes.
Hale, Benjamin G.
core
Latent viral infections in young patients with inflammatory diseases treated with biological agents:prevalence of JC virus genotype2 [PDF]
Treatment with biological drugs is associated with increased susceptibility to viral infections. Reactivation of JC virus (JCV) and human cytomegalovirus (HCMV) in adults after therapy has been documented.
D'AGARO, PIERLANFRANCO +10 more
core +1 more source
Virus Epstein Barr (VEB) ha sido relacionado con una serie de tumores malignos de origen epitelial y linfoide. Existe una clara correlación entre este virus y enfermedades linfoproliferativas como Linfoma de Burkitt (LB), Linfoma Hodgkin (LH), Linfoma no
Sunny Sánchez-Giler +8 more
doaj +1 more source
EpsteinBarr virus-encoded small RNAs (EBERs) do not modulate interferon effects in infected lymphocytes [PDF]
The recent derivation of otherwise isogenic Epstein-Barr virus (EBV) recombinants carrying or lacking the EBV small RNA (EBER) genes enabled us to test whether EBERs are similar to adenovirus VA RNAs in modulating interferon (IFN) effects on virus ...
Sankar Swaminathan +3 more
core

