Results 51 to 60 of about 3,772 (169)

Successful Aspiration Thrombectomy for Cocaine‐Induced Right Coronary Artery Embolism Secondary to Left Ventricular Thrombus: A Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 5, May 2025.
ABSTRACT Coronary embolism (CE) is a rare yet significant contributor to acute myocardial infarction (AMI), particularly in younger patients. We report a 42‐year‐old male who experienced an AMI following recent cocaine use. Investigations revealed a left ventricular apical thrombus, identified as the source of a distal embolus occluding the right ...
Abraam Rezkalla, Ahmad Nouri, Fadi Hadya, Islam Rajab, Emile Doss   +4 more
wiley   +1 more source

Antithrombotic use in retinal artery occlusion: A narrative review

The Kaohsiung Journal of Medical Sciences, Volume 41, Issue 4, April 2025.
Abstract Retinal artery occlusion (RAO) is a critical ophthalmic emergency with a high risk of significant visual impairment. While traditional treatment aims to promptly restore blood flow to the retina, recent research has investigated the potential benefits of anticoagulation therapy for managing this condition. This paper reviews current literature
Wan‐Yu Liu, Yun‐Hsin Tang, Yi‐Hsing Chen   +2 more
wiley   +1 more source

Platelet aggregation inhibition by Eptifibatide versus high dose Tirofiban during primary percutaneous interventions

The Egyptian Heart Journal, 2014
Background: Platelet aggregation occurs as a central role in acute coronary syndrome (ACS), and glycoprotein GP IIb/IIIa inhibitors may enhance the benefits expected from early recanalisation. Aim: To compare the degree of platelet aggregation inhibition
Yasser Sadek Nassar, Mohamed Laimud, Mohamed Afify, Mohamed Ashraf Shawky   +3 more
doaj   +1 more source

Microfluidic thrombosis under multiple shear rates and antiplatelet therapy doses. [PDF]

PLoS ONE, 2014
The mainstay of treatment for thrombosis, the formation of occlusive platelet aggregates that often lead to heart attack and stroke, is antiplatelet therapy. Antiplatelet therapy dosing and resistance are poorly understood, leading to potential incorrect
Melissa Li, Nathan A Hotaling, David N Ku, Craig R Forest   +3 more
doaj   +1 more source

Association of Anaesthetists guidelines: the use of blood components and their alternatives

Anaesthesia, Volume 80, Issue 4, Page 425-447, April 2025.
Summary Background The administration of blood components and their alternatives can be lifesaving. Anaemia, bleeding and transfusion are all associated with poor peri‐operative outcomes. Considerable changes in the approaches to optimal use of blood components and their alternatives, driven by the findings of large randomised controlled trials and ...
Akshay Shah, Andrew A. Klein, Seema Agarwal, Andrew Lindley, Aamer Ahmed, Kerry Dowling, Emma Jackson, Sumit Das, Divya Raviraj, Rachel Collis, Anna Sharrock, Simon J. Stanworth, Paul Moor   +12 more
wiley   +1 more source

Comparison between Intracoronary Abciximab and Intravenous Eptifibatide Administration during Primary Percutaneous Coronary Intervention of Acute ST-Segment Elevation Myocardial Infarction

Journal of Tehran University Heart Center, 2015
Background: Administration of glycoprotein IIb/IIIa inhibitors is an effective adjunctive treatment strategy during primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI).
MohammadHasan Namazi, Morteza Safi, Hosein Vakili, Habibollah Saadat, Esfandiar Karimi, Ramin Khameneh-Bagheri   +5 more
doaj  

A novel strategy for site selective spin-labeling to investigate bioactive entities by DNP and EPR spectroscopy

Scientific Reports, 2021
A novel specific spin-labeling strategy for bioactive molecules is presented for eptifibatide (integrilin) an antiplatelet aggregation inhibitor, which derives from the venom of certain rattlesnakes.
Kevin Herr, Max Fleckenstein, Martin Brodrecht, Mark V. Höfler, Henrike Heise, Fabien Aussenac, Torsten Gutmann, Michael Reggelin, Gerd Buntkowsky   +8 more
doaj   +1 more source

Impact of bridging thrombolysis versus endovascular thrombectomy alone on outcomes in anticoagulated patients with atrial fibrillation and acute ischaemic stroke

European Journal of Neurology, Volume 31, Issue 12, December 2024.
Abstract Background and purpose The impact of bridging thrombolysis prior to endovascular thrombectomy (EVT) compared to EVT alone on intracerebral haemorrhage (ICH), subarachnoid haemorrhage (SAH), and death in anticoagulated atrial fibrillation (AF) patients with acute ischaemic stroke (AIS) is not well defined.
Muath Alobaida, Stephanie L. Harrison, Deirdre A. Lane, Fiona Rowe, Philip Austin, Azmil H. Abdul‐Rahim, Gregory Y. H. Lip   +6 more
wiley   +1 more source

Before, during, and after: An Argument for Safety and Improved Outcome of Thrombolysis in Acute Ischemic Stroke with Direct Oral Anticoagulant Treatment

Annals of Neurology, Volume 96, Issue 5, Page 871-886, November 2024.
Clinicians fear thrombolysis after direct oral anticoagulant (DOAC) use due to experience with warfarin. In contrast to vitamin K antagonists such as warfarin, DOACs prevent thrombosis by blocking thrombin. Clinical observational data suggest that thrombolysis may be safe in the setting of DOAC use.
Sanaz Monjazeb, Heather V. Chang, Patrick D. Lyden   +2 more
wiley   +1 more source

A critical review of therapeutic interventions in sickle cell disease: Progress and challenges

Archiv der Pharmazie, Volume 357, Issue 11, November 2024.
Sickle cell disease reflects a complex interplay of genetics, hematology, and clinical symptoms. The intricate pathogenesis of the disease offers a landscape with various targets and treatment options. Anticipated advancements in treatment include combining fetal hemoglobin inducers with other drug classes to improve the efficacy beyond monotherapy ...
Chandu Ala, Renuka Parshuram Joshi, Pragya Gupta, Sangam Giri Goswami, Sivaprakash Ramalingam, Chandra Sekhar Kondapalli Venkata Gowri, Murugesan Sankaranarayanan   +6 more
wiley   +1 more source