Results 101 to 110 of about 127,286 (242)

Caregiver outcomes (hours, ZBI, EQ-VAS, EQ-5D-3L) by patient dementia severity.

, 2018
Caregiver outcomes (hours, ZBI, EQ-VAS, EQ-5D-3L) by patient dementia severity.
Xiaohan Hu (1674277), Rezaul K. Khandker (6057944), Eddie Jones (5169761), Baishali M. Ambegaonkar (6057947), Robert Wood (532666), Craig W. Ritchie (523910), Christopher M. Black (2504350)   +6 more
core   +1 more source

Comparing responsiveness of the EQ-5D-5L, EQ-5D-3L and EQ VAS in stroke patients [PDF]

, 2015
Aims: To date, evidence to support the construct validity of the EQ-5D-5L has primarily focused on cross-sectional data. The aims of this study were to examine the responsiveness of EQ-5D-5L in patients with stroke and to compare it with responsiveness ...
Buczek, J, Janssen, MF (Bas), Karlinska, A, Kobayashi, A. (Adam), Niewada, M. (Maciej), Buczek, J. (Julia), Niewada, M, Golicki, D, Janssen, M.F. (Bas), Pickard, A.S. (Simon), Kobayashi, A, Karlińska, A. (Anna), Golicki, D. (Dominik), Pickard, AS   +13 more
core   +2 more sources

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Validity and reliability of the EQ-5D-3L™ among a paediatric injury population [PDF]

Health and Quality of Life Outcomes, 2013
The purpose of this study was to determine the construct validity of the EQ-5D-3L™ for use among a population of injured young people and to examine the reliability of different modes of administration including paper and pencil, online and telephone. Methods: In total, 345 participants (aged 0 – 16) were recruited from a paediatric hospital in a large
Brussoni, Mariana, Kruse, Sami, Walker, Kerry   +2 more
openaire   +2 more sources

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

A comparison of values in the EQ-5D-3L value set and the EQ-5D-5L crosswalk value set for Trinidad and Tobago.

, 2019
A comparison of values in the EQ-5D-3L value set and the EQ-5D-5L crosswalk value set for Trinidad and Tobago.
Althea La Foucade (6645668), Henry Bailey (6645662), Paul Kind (6645671), Mathieu F. Janssen (6645665)   +3 more
core   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Convergent validity of the EQ-5D-3L in a randomized-controlled trial of the Housing First model

BMC Health Services Research, 2019
Background Health utility assessments are important for economic evaluations but few instruments have been validated in homeless people with mental illness.
Nicole Kozloff, Andrew D. Pinto, Vicky Stergiopoulos, Stephen W. Hwang, Patricia O’Campo, Ahmed M. Bayoumi   +5 more
doaj   +1 more source

International Valuation Protocol for the EQ-5D-Y-3L [PDF]

, 2020
Ramos-Goni JM, Oppe M, Stolk E, et al. International Valuation Protocol for the EQ-5D-Y-3L. PharmacoEconomics. 2020;38:653-663.The EQ-5D-Y-3L is a generic, health-related, quality-of-life instrument for use in younger populations.
Oppe, M, Devlin, Nancy, Stolk, E, Rivero-Arias, O, Oppe, Mark, Ramos-Goñi, JM, Kreimeier, Simone ; https://orcid.org/, Ramos-Goni, Juan M, Nancy, Devlin, Kreimeier, Simone, Juan M., Ramos-Goni, Mark, Oppe, Shah, Koonal, Rivero-Arias, Oliver, Devlin, N, Kreimeier, S, Stolk, Elly, Rivero Arias, Oliverio, Shah, K   +18 more
core   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source