Results 181 to 190 of about 39,716 (256)

Impairment in quality of life with different sport orthopaedic musculoskeletal injuries—A comprehensive analysis of the German arthroscopy register

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim of this study was to identify the impairment of quality of life (QoL) for different sport orthopaedic injuries prior to surgery in Germany and build a baseline dataset for these injuries. Methods Data from the German arthroscopy registry (DART) between November 2017 and January 2025 were used.
Dominik Szymski, Christoph Lutter, Sina Graeber, Alexander‐Stephan Henze, Maximilian Hinz, Anja Hirschmueller, Thomas Niethammer, Ralf Mueller Rath, Thomas Tischer   +8 more
wiley   +1 more source

Developing mapping algorithms to predict EQ-5D health utility values from Bath Ankylosing Spondylitis Disease Activity Index and Bath Ankylosing Spondylitis Functional Index among patients with Ankylosing Spondylitis

Health and Quality of Life Outcomes
Background Preference-based measures of health-related quality of life (HRQoL), such as the EQ-5D or the SF-6D, are essential for health economic evaluation. However, they are rarely included in clinical trials of ankylosing spondylitis (AS).
Lingjia Yu, Huizhi Yang, Liyong Lu, Yingying Fang, Xianyu Zhang, Shunping Li, Chaofan Li   +6 more
doaj   +1 more source

Patients with previous anterior cruciate ligament reconstruction achieve equally good outcomes after total knee arthroplasty: A Swedish registry‐based study of 7755 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Patients who have undergone anterior cruciate ligament reconstruction (ACLR) may later require total knee arthroplasty (TKA) due to osteoarthritis (OA). The impact of previous ACLR on patient‐reported outcomes (PROs) after TKA remains uncertain.
Ioannis Syrikas, Ioannis Karikis, Neel Desai, Georgios Tsikandylakis   +3 more
wiley   +1 more source

Multi-task learning for predicting quality-of-life and independence in activities of daily living after stroke : a proof-of-concept study [PDF]

A health-related (HR) profile is a set of multiple health-related items recording the status of the patient at different follow-up times post-stroke. In order to support clinicians in designing rehabilitation treatment programs, we propose a novel multi ...
Garcia-Rudolph, Alejandro, Kelleher, John D., Nguyen, Thi Nguyet Que, Saurí, Joan   +3 more
core   +1 more source

Rehabilitation paired with vagus nerve stimulation for motor function of chronic ischemic stroke patients in China: Study protocol of a multicenter randomized controlled trial (Repair Study)

Neuroprotection, EarlyView.
Mechanism of vagus nerve stimulation (VNS) paired with movement: VNS activates cholinergic nucleus basalis and noradrenergic locus coeruleus neurons, modulating motor cortex activity (light green and red areas) in a task‐specific manner during targeted movements. VNS: vagus nerve stimulation.
Anchao Yang, Yong Liu, Hongxing Huang, Xiaoqin Sun, Dawei Zang, Jun Lu, Qingping Tang, Yulian Zhu, Qi Yue, Weining Wang, Guohui Lu, Lang Shuai, Jun Wang, Yunqian Li, Li Bie, Zhenlan Li, Guoxing Xu, Jinghui Li, Tao Ding, Yanwu Guo, Wen Wu, Yuting Xu, Yuanxiang Lin, Zhiyong Wang, Fuxin Lin, Chunhua Hang, Rong Xu, Xiangyu Liu, Wenjun Hong, Kai Shu, Min Lu, Feng Hu, Ruobing Qian, Ming Wu, Liuzhong Sun, Min Wu, Yingchuan Chen, Qian Wang, Sihao Liu, Qiao Zhang, Shiyi Zuo, Binxia Zhang, Wei Wu, Zhongming Wang, Huayang Deng, Lijuan Quan, Renli Qi, Wei Wang, Fuchuan Huang, Xiemin Liang, Feng Wang, Yalan Wang, Zejian Chen, Jiang Ran, Liang Chen, Jianguo Zhang, Ying Mao   +56 more
wiley   +1 more source

Health-state utility values and their time to deterioration in informal caregivers of older patients with chronic diseases

Frontiers in Public Health
ObjectivesThis study aimed to assess health state utility values (HSUVs) in caregivers of older patients with chronic diseases receiving or not receiving social worker support.MethodsThis multicentric open-label randomized study assigned caregivers to ...
Astrid Pozet, Antoine Falcoz, Cécile Roller, Taha Jai, Aurelia Meurisse, Virginie Nerich   +5 more
doaj   +1 more source

Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short‐Chain Fatty Acids

Phytotherapy Research, EarlyView.
Baicalin restores the hypoglycemic effect of metformin by decreasing the serum imidazole propionate. ABSTRACT Gut microbiota dysbiosis is implicated in metformin non‐response. This study aimed to investigate whether baicalin, a microbiota‐modulating flavonoid derived from Radix Scutellariae, could restore metformin sensitivity and explored the ...
Aiting Wang, Zenghui Miao, Bangrong Huang, Jiayu Zeng, Mingxia Yuan, Dan Yan   +5 more
wiley   +1 more source

Conductive Hydrogel‐Enabled Electrode for Scalp Electroencephalography Monitoring

Small Methods, EarlyView.
Conductive hydrogels are emerging as effective EEG electrode‐scalp interfaces to overcome hair barriers. This review presents the demanding parameters for hair‐compatible hydrogel electrodes and summarizes their applications in healthcare and brain‐computer interfaces.
Zichong Ji, Leqi Li, Meiqiong Zheng, Xinyuan Ye, Wenqing Yan, Zonglei Wang, Yi Liu, Yuli Wang, Yujie Zhang, Pengcheng Zhou, Jiawei Yang, Mingzhe Wang, Shihong Lin, Hossam Haick, Yan Wang   +14 more
wiley   +1 more source

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie, Shan Jin, Yao Zhan, Tiantian Du, Yaqi Dong, Peilong Li, Xiaoshi Zhang, Qiuchen Qi, Jie Gao, Chuanxin Wang   +9 more
wiley   +1 more source

Impact of cardiovascular disease on health-related quality of life among older adults in eastern China: evidence from a national cross-sectional survey

Frontiers in Public Health
ObjectiveThis study explores the health-related quality of life (HRQoL) scores of Chinese older adults with Cardiovascular Disease(CVD) using the EQ-5D-3L, the aim of this study is to investigate the association between health and HRQoL in older adults ...
Leping Wan, Leping Wan, Guangmei Yang, Guangmei Yang, Haiying Dong, Xiaoxiao Liang, Yan He   +6 more
doaj   +1 more source