Results 201 to 210 of about 39,716 (256)

Impact of geriatric impairments on outcomes of single‐agent immunotherapy in solid tumors

International Journal of Cancer, Volume 158, Issue 5, Page 1370-1382, 1 March 2026.
What's New? This study comprehensively assesses the impact of frailty and geriatric impairments on key clinical outcomes of single‐agent immunotherapy in older adults with solid tumors. Using prospective multicenter data, the authors demonstrate that frailty is significantly associated with higher rates of all‐cause hospitalization and mortality ...
Asli Özkan, Karlijn de Joode, Ellen Kapiteijn, Marije Slingerland, Stephanie Zunder, Frederiek van den Bos, Simon Mooijaart, Anna Uit den Boogaard, Stella Trompet, Hans Westgeest, Astrid van der Veldt, Ron H. J. Mathijssen, Geert Labots, Cynthia Holterhues, Els M. E. Verdegaal, Nienke A. de Glas, Johanneke E. A. Portielje   +16 more
wiley   +1 more source

Personalized care of paediatric drug‐resistant epilepsy in Africa: A single‐centre pilot study utilizing mobile health and genetic testing

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 394-406, March 2026.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70075 This original article is commented on by Mante on pages 307–308 of this issue. Abstract Aim To evaluate personalized care or precision medicine initiatives, including mobile health (mHealth) technology and genetic screening, in a South African paediatric epilepsy clinic ...
Ian S. Olivier, Karen Fieggen, Sandra Komarzynski, Elin H. Davies, Irene Muchada, Caitlin McIntosh, Alina Esterhuizen, Richard J. Burman, Jo M. Wilmshurst, and the University of Cape Town (UCT) Human Genetics Precision Medicine Epilepsy Group, Nicholas Loxton, Shrinav R Dawlatt, Akshay Vanmali   +12 more
wiley   +1 more source

Sensitivity analysis of EQ-5D-3L index scores in terms of discriminative and known-groups validity in SLE: introducing Adequate Health State. [PDF]

Rheumatology (Oxford), 2023
Hua N, Gomez A, Lindblom J, Emamikia S, Enman Y, Grannas D, Heintz E, Regardt M, Parodis I.   +8 more
europepmc   +1 more source

Impact of Lymphedema on Women's Lives After Gynaecological Cancer: An Integrative Review

Scandinavian Journal of Caring Sciences, Volume 40, Issue 1, March 2026.
ABSTRACT Background Secondary Lower‐Limb Lymphedema (LLL) is a frequent, progressive late effect affecting women after gynaecological cancer treatment, causing swelling due to fluid accumulation in the interstitial spaces in the lower extremities, the lower abdomen, hips and genitals. There is no consensus on how to define and quantify LLL, which makes
Pernille Dehn, Anette Rasmussen, Lene Seibæk, Ragnhild Johanne Tveit Sekse, Anne Marie Thimm, Mette Linnet Olesen   +5 more
wiley   +1 more source

Capturing Valuation Study Sampling Uncertainty in the Estimation of Health State Utility Values Using the EQ-5D-3L [PDF]

Objectives: Utility scores associated with preference-based health-related quality-of-life instruments such as the EQ-5D-3L are reported as point estimates.
Baio, Gianluca, Poulimenos, Spyridon, Round, Jeff   +2 more
core  

Thermal Phase‐Modulation of Thickness‐Dependent CVD‐Grown 2D In2Se3

Advanced Functional Materials, Volume 36, Issue 12, 9 February 2026.
A comprehensive study of CVD‐grown 2D In2Se3 reveals a distinct thickness‐dependent phase landscape and a reversible, thermally driven transformation between β″ and β* variants. In situ TEM electron diffraction and Raman spectroscopy reveal structural dynamics, while the structural invariance of the α‐phase in ultrathin regimes highlights its stability—
Dasun P. W. Guruge, Zhenhuan Chen, Joseph F. S. Fernando, Chao Zhang, Liangzhi Kou, Konstantin L. Firestein, Dmitri V. Golberg   +6 more
wiley   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, Volume 13, Issue 8, 9 February 2026.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

Health-related quality of life in racial and ethnic minority adults with type 2 diabetes: validity and responsiveness of the EQ-5D-3L. [PDF]

Qual Life Res
Joshi M, Pickard AS, Kim K, Sharp LK, Gerber BS, Touchette DR.   +5 more
europepmc   +1 more source

Health Status Outcomes after Computed Tomography or Invasive Coronary Angiography for Stable Chest Pain:A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial

Importance: The effect of computed tomography (CT) vs invasive coronary angiography (ICA) on health status outcomes is unknown. Objective: To evaluate CT and ICA first-test strategies on quality of life (QOL) and angina. Design, Setting, and Participants:

core   +2 more sources

Solar‐Blind Ultraviolet Photodetectors Based on Two‐Dimensional Materials and Their Heterostructures

Advanced Physics Research, Volume 5, Issue 2, February 2026.
Solar‐blind ultraviolet photodetectors are crucial for diverse applications. This review comprehensively summarizes recent advances using two‐dimensional materials and their heterostructures, which offer tunable bandgaps, flexibility, and no lattice‐matching constraints.
Yu Lu, Junming Song, Xiarui Wu, Junpeng Lu, Zhenhua Ni, Weiwei Zhao, Fang Yang, Hongwei Liu   +7 more
wiley   +1 more source