Results 141 to 150 of about 35,541 (284)

Appropriateness of the EQ-5D-5L in capturing health-related quality of life in individuals with transfusion-dependent β-thalassemia: a mixed methods study

Health and Quality of Life Outcomes
Background Individuals with transfusion-dependent β-thalassemia (TDT) experience symptoms and functional impacts that reduce their health-related quality of life.
Adriana Boateng-Kuffour, Hanna Skrobanski, Jennifer Drahos, Puja Kohli, Katie Forster, Sarah Acaster, Zahra Pakbaz, Nanxin Li, Kate Williams   +8 more
doaj   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Validity of the Eq-5d-5l in Stroke Patients [PDF]

Value in Health, 2014
Golicki, D., Niewada, M., Buczek, J., Karlinska, A., Kobayashi, A., Janssen, M.F., Pickard, A.S.   +6 more
openaire   +2 more sources

The EQ-5D-5L valuation study for Trinidad and Tobago

Health and Quality of Life Outcomes
AbstractPurposeThe 2016 EQ-5D-3L value set for Trinidad and Tobago (T&T) allows for the calculation of EQ-5D-5L values via the crosswalk algorithm. The 2016 value set was based on methods predating the EQ-VT protocol, now considered the gold standard for developing EQ-5D value sets.
Henry Bailey, Marcel F. Jonker, Eleanor Pullenayegum, Fanni Rencz, Bram Roudijk   +4 more
openaire   +3 more sources

Empowering citizens to spontaneously report suspected adverse drug reaction: Systematic literature review of interventions and their impact

British Journal of Clinical Pharmacology, EarlyView.
This systematic literature review aimed to identify and characterize existing interventions designed to empower citizens to spontaneously report adverse drug reactions (ADRs) and to determine which interventions have been shown to be the most effective internationally. The research question was structured using the PICO framework.
Margarida Perdigão, Ana Margarida Advinha, Manuel José Lopes, Sofia de Oliveira Martins   +3 more
wiley   +1 more source

Management of multimorbidity using a patient-centred care model:a pragmatic cluster-randomised trial of the 3D approach [PDF]

, 2018
Background: The management of people with multiple chronic conditions challenges health-care systems designed around single conditions. There is international consensus that care for multimorbidity should be patient-centred, focus on quality of life ...
Bower, Peter, Brookes, Sara, Chaplin, Katherine, Fitzpatrick, Bridie, Gardner, Caroline, Gaunt, Daisy M., Guthrie, Bruce, Hollinghurst, Sandra, Lee, Victoria, Man, Mei-See, Mann, Cindy, McLeod, John, Mercer, Stewart W., Moffat, Keith R., Salisbury, Chris   +14 more
core   +9 more sources

Synthesis of Single‐Crystalline Ni‐Rich Cathodes for Lithium‐Ion Batteries With Superior High‐Voltage Stability by Mo/Nb Dual Doping

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A novel synthesis method of single‐crystalline LiNi0.8Co0.15Al0.05O2 (NCA) is introduced, involving the stripping of grain boundaries from polycrystalline NCA (PC‐NCA) during Mo/Nb co‐doping. Mo doping near the grain surface significantly reduces parasitic interface reactions and inhibits the excessive growth of CEI films, while Nb doping within the ...
Guomeng Xie, Ziqin Xu, Delai Qian, Ruiwu Li, Qingsong Hua, Shun Lu, Haitao Fang   +6 more
wiley   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Testing the Psychometric Properties of 9 Bolt-Ons for the EQ-5D-5L in a General Population Sample [PDF]

Objectives: We aimed to assess the psychometric performance and added value of 9 existing bolt-ons (breathing problems, cognition, hearing, self-confidence, skin irritation, sleep, social relationships, tiredness, and vision) for the EQ-5D-5L in a ...
Janssen, Mathieu F., Rencz, Fanni
core   +3 more sources

Scale and rate heterogeneity in the EQ-5D-5L valuation

Health and Quality of Life Outcomes
Abstract Objectives To estimate values on a quality-adjusted life year (QALY) scale using individual preference evidence, choice analyses typically include ancillary parameters, such as scale factors and discount rates. These parameters potentially differ among respondents.
Maksat Jumamyradov, Benjamin M. Craig, Michał Jakubczyk   +2 more
openaire   +3 more sources