Results 201 to 210 of about 134,162 (275)

Economic Evaluation of the RETURN Intervention to Increase Routine Dental Attendance Among Disadvantaged Adults: Net Health Benefit (QALYs) and Patient Cost Outcomes From a Randomised Controlled Trial

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives Routine dental attendance is associated with better health outcomes, yet those from disadvantaged backgrounds are more likely to seek problem‐driven, episodic care. The RETURN intervention, a brief behavioural intervention delivered by dental nurses in urgent care, was designed to support urgent care users to take up planned dental ...
Tayamika Zabula, Victoria Lowers, Dan Howdon, Rebecca Harris   +3 more
wiley   +1 more source

Population norms for the EQ-5D-3L and EQ-5D-5L in Peninsular Malaysia. [PDF]

Qual Life Res
Vasan Thakumar A, Li X, Shafie AA, Cheng LJ.   +3 more
europepmc   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

Cell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang, Yucheng Gao, Shuhang Dong, Shuanggong Liu, Lei Liu, Ziyi Song, Jie Xu, Yijun Rong, Guangxu Song, Yingze Zhang, Dongjin Wu, Zengxin Gao   +11 more
wiley   +1 more source

Comparative performance of EQ-5D-5L bolt-ons in China and the Netherlands: results from the EQ-DAPHNIE project. [PDF]

Qual Life Res
Cho SH, Janssen MF, Al Sayah F, Mao Z, Feng YS, Kemény LV, Rencz F, EQ-DAPHNIE Project Team.   +7 more
europepmc   +1 more source

Evaluation of a secondary care multidisciplinary clinic for adults with early‐onset type 2 diabetes at high risk in Leicester, Leicestershire and Rutland

Diabetic Medicine, EarlyView.
Abstract Background Clinical services for adults with early‐onset type 2 diabetes (EOT2D) are in urgent need of improvement. Methods We evaluated a multi‐disciplinary clinic for individuals with EOT2D at high risk (HbA1c >9%/triglyceride >20 mmol/L), providing 2–3 flexibly arranged consultations per individual between March 2024 and September 2025 ...
Jonathan Goldney, Malak Hamza, Priscilla Sarkar, Harriet Morgan, Nicole Green, James Ridgeway, Victoria Alabraba, Laura Willcocks, Krupali Chandracant, Kashmala Javed, Rhys O'Callaghan, Finley Turner, Samuel Seidu, Claire L. Meek, Melanie J. Davies   +14 more
wiley   +1 more source

Health-related quality of life in breast cancer measured with EQ-5D-5L. [PDF]

J Patient Rep Outcomes
Torres S, Trudeau M, Liu G, Mitsakakis N, Bayoumi AM.   +4 more
europepmc   +1 more source

The impact of frailty on glycaemic control in older adults with type 1 diabetes: An observational study

Diabetic Medicine, EarlyView.
Abstract Aims The type 1 diabetes population is ageing. Frailty is the age‐related physiological decline that occurs across organ systems, increasing the body's vulnerability to stressors. Current consensus‐based guidelines, derived from evidence in type 2 diabetes, prioritise hypoglycaemia avoidance, which increases falls, hospitalisation and ...
Jonathan A. Golding, Scarlett O. Long, Suzy V. Hope, Juliet E. Wright, Ali J. Chakera, Tom J. Levett   +5 more
wiley   +1 more source

A direct comparison of the measurement properties of the PROMIS-16 and EQ-5D-5L in the U.S. general population. [PDF]

Qual Life Res
Pham M, Craig BM, Peasgood T, Rencz F.
europepmc   +1 more source

DiaActive protocol: A randomized controlled trial of cognitive‐motor multicomponent exercise to reduce fall rate in older adults with diabetes

Diabetic Medicine, EarlyView.
Abstract Introduction Older adults with diabetes have an increased risk of falls due to neuropathy, impaired bone health and cardiovascular disease, resulting in significant morbidity and mortality. Conventional fall‐prevention programmes primarily target strength and balance, while cognitive‐motor integration, essential for safe mobility in complex ...
Aksayan Arunanthy Mahalingasivam, Asger Ahlmann Bech, Peter Vestergaard, Martin Grønbech Jørgensen, Nicklas Højgaard‐Hessellund Rasmussen   +4 more
wiley   +1 more source

Efficacy and Safety of Crisugabalin for Inadequately Controlled Diabetic Peripheral Neuropathic Pain: A Randomized, Active‐Controlled, Phase 2 Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Crisugabalin (HSK16149), a selective γ‐aminobutyric acid (GABA) analog, has shown preliminary efficacy in controlling diabetic peripheral neuropathic pain (DPNP), but efficacy in patients with inadequate response to prior pregabalin treatment remains unknown. Materials and Methods This multicentre randomized controlled trial was conducted
Yaming Li, Fang Zhang, Wei Liu, Xiuhai Su, Bin Zhou, Na Xu, Junjie Shang, Chen Fang, Liujun Fu, Fangqiong Li, Chao Zheng, Jinyou Duan   +11 more
wiley   +1 more source