Results 211 to 220 of about 35,541 (284)

Toward a validated European instrument to measure the socioeconomic impact of cancer

International Journal of Cancer, Volume 158, Issue 12, Page 3288-3299, 15 June 2026.
What's new? The Financial Index of Toxicity (FIT) evaluates patients' experiences of financial strain after cancer diagnosis. Originally developed in Canada for head and neck cancer patients, the applicability of FIT to other populations remains uncertain. This study assessed the validity of FIT in Europe using patient‐level data from six countries and
Jasper Ubels, Julie M. Vancoppenolle, Josephine Tetteh, Wim H. van Harten, Valesca P. Retèl, Michael Schlander, Nora Franzen   +6 more
wiley   +1 more source

A comparative study of EQ-5D-5L and SF-6D scales based on patients receiving oral anticoagulant therapy. [PDF]

Health Qual Life Outcomes
Dong S, Li Y, Liao Z, Lin Q, Yiu HHE, Ming WK, Li L, Zhao R.   +7 more
europepmc   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1522-1536, June 2026.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

Validity of EQ-5D-5L breathing and cognition bolt-ons in non-hospitalized patients after COVID-19. [PDF]

Qual Life Res
Stavem K, Garratt AM.
europepmc   +1 more source

Does Digital Make a Difference? Willingness‐to‐Pay for Digital Versus Offline Weight Loss in Germany

Obesity Science &Practice, Volume 12, Issue 3, June 2026.
ABSTRACT Background Germany introduced both digital health applications (DiGA) and an “offline” structured disease management program (DMP) for obesity within statutory health insurance. Given limited resources and ongoing reimbursement decisions, evidence on how individuals with obesity assessed the value of intervention delivery in terms of their ...
Kevin Helms, Stefan K. Lhachimi, Wolf Rogowski, Oliver Lange   +3 more
wiley   +1 more source

Derivation of a South African tariff for the EQ-5D-5L using a personal utility function approach. [PDF]

Int J Technol Assess Health Care
Moolla A, Schneider P, Hofman K, Goldstein SJ, Thsehla E, Dixon S.   +5 more
europepmc   +1 more source

Acute‐Care Utilization and Cost Offsets Associated With Language‐Concordant, Pharmacist‐Integrated Care Management Among High‐Need, High‐Cost Adults

Health Services Research, Volume 61, Issue 3, June 2026.
ABSTRACT Objective To estimate utilization and economic effects of a language‐concordant, pharmacist‐integrated care‐management program and examine equity by language and insurance. Study Setting and Design We conducted a retrospective cohort study emulating a target trial across four Phoenix safety‐net clinics (March 2022–September 2023) using inverse
Sasha R. Sioni, Lesley Manson, Nicholas Arledge, Janice Yanez, Mohammad Al Mouslmani   +4 more
wiley   +1 more source

Identifying and developing EQ-5D-5L bolt-on items for Chinese chronic obstructive pulmonary disease patients. [PDF]

Health Qual Life Outcomes
Feng J, Luo N, Zhang C, Jiang Y, Chen G, Yang Z, Mao Z, Wang J, An J, Li S.   +9 more
europepmc   +1 more source

RORA Targeting PRNP Modulates Age‐Related Cataract via Activation Oxidative Injury‐Induced Cellular Senescence and Apoptosis of Lens Epithelial Cells

Aging Cell, Volume 25, Issue 6, June 2026.
The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou, Wanqian Li, Jiaojiao Zhang, Chao Cen, Wanqiu Zheng, Ruonan Li, Hong Cheng, Liang Liang, Juan Kang, Wenjuan Wan, Ke Hu, Shijie Zheng   +11 more
wiley   +1 more source

Biases in the measurement of health-related quality of life in the EQ-5D-5L among those with serious physical traumatic injuries: the ADVANCE cohort study. [PDF]

Qual Life Res
Dyball D, Schofield S, Burdett H, LeFeuvre P, Bennett AN, Cullinan P, Boos CJ, Bull AMJ, Fear NT.   +8 more
europepmc   +1 more source