Results 1 to 10 of about 40,172 (233)
Whole-organism eQTL mapping at cellular resolution with single-cell sequencing
eLife, 2021 Genetic regulation of gene expression underlies variation in disease risk and other complex traits. The effect of expression quantitative trait loci (eQTLs) varies across cell types; however, the complexity of mammalian tissues makes studying cell-type ...
Eyal Ben-David +5 more
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eQTL regulates OsHAK5 in enhancing potassium content under salt stress in rice
Electronic Journal of Plant Breeding, 2023 To alleviate salt stress in rice, the role of potassium in countering the ill effects of sodium is gaining importance. Towards this, OsHAK5 a member of the high-affinity potassium transporter family was known for enhancing the intracellular potassium ...
Akshara Balachandra1, Varanavasiappan Shanmugam1, Kumar K. Krish1, Ravichandran Veerasamy2, Kokiladevi Easwaran1, Kaleeswari Ramaiah Kutralingam3, Sudhakar Duraialagaraja1, Arul Loganathan1*
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Impact of natural genetic variation on gene expression dynamics. [PDF]
PLoS Genetics, 2013 DNA sequence variation causes changes in gene expression, which in turn has profound effects on cellular states. These variations affect tissue development and may ultimately lead to pathological phenotypes.
Marit Ackermann +2 more
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A statistical framework for joint eQTL analysis in multiple tissues [PDF]
, 2012 Mapping expression Quantitative Trait Loci (eQTLs) represents a powerful and widely-adopted approach to identifying putative regulatory variants and linking them to specific genes.
Flutre, Timothée +3 more
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G3: Genes, Genomes, Genetics, 2020 Seed germination is characterized by a constant change of gene expression across different time points. These changes are related to specific processes, which eventually determine the onset of seed germination.
Margi Hartanto +8 more
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Identification of asthma-related genes using asthmatic blood eQTLs of Korean patients
BMC Medical Genomics, 2023 Background More than 200 asthma-associated genetic variants have been identified in genome-wide association studies (GWASs). Expression quantitative trait loci (eQTL) data resources can help identify causal genes of the GWAS signals, but it can be ...
Dong Jun Kim +12 more
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Expression quantitative trait locus studies in the era of single-cell omics
Frontiers in Genetics, 2023 Genome-wide association studies have revealed that the regulation of gene expression bridges genetic variants and complex phenotypes. Profiling of the bulk transcriptome coupled with linkage analysis (expression quantitative trait locus (eQTL) mapping ...
Jie Luo +5 more
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BioData Mining, 2021 Background Genomic studies increasingly integrate expression quantitative trait loci (eQTL) information into their analysis pipelines, but few tools exist for the visualization of colocalization between eQTL and GWAS results.
Theodore G. Drivas +2 more
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Scientific Reports, 2022 Colorectal cancer (CRC) is characterised by heritable risk that is not well understood. Heritable, genetic variation at 11q23.1 is associated with increased colorectal cancer (CRC) risk, demonstrating eQTL effects on 3 cis- and 23 trans-eQTL targets.
Bradley T. Harris +9 more
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Dissecting the eQTL Micro-Architecture in Caenorhabditis elegans
Frontiers in Genetics, 2020 The study of expression quantitative trait loci (eQTL) using natural variation in inbred populations has yielded detailed information about the transcriptional regulation of complex traits.
Mark G. Sterken +6 more
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