Results 141 to 150 of about 48,393 (270)

Potential Targets Related to Skin Aging: Based on eQTL and GWAS Datasets

Clinical, Cosmetic and Investigational Dermatology
Hanping Shi,1,2 Xianwei Cao1– 3 1School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China; 2Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University,
Shi H, Cao X
doaj  

eQTL Viewer: visualizing how sequence variation affects genome-wide transcription

BMC Bioinformatics, 2007
Background Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expression profiles are related with sequence polymorphisms across the genome ...
Zeng Zhao-Bang, Aylor David L, Zou Wei
doaj   +1 more source

Genome‐Wide Association Study Elucidates the Genetic Architecture of Manganese Tolerance in Brassica napus

Plant, Cell &Environment, EarlyView.
ABSTRACT Brassica napus (canola) is a significant contributor to the world's oil production and is cultivated across continents, yet acidic soils with aluminium (Al3+) and manganese (Mn2+) toxicities limit its production. The genetic determinants underlying natural variation for acidic soil tolerance in canola are unknown and need to be determined ...
Harsh Raman, Zetao Bai, Brett McVittie, Sourav Mukherjee, Hugh D. Goold, Yuanyuan Zhang, Nay Chi Khin, Yu Qiu, Nawar Shamaya, Shengyi Liu, Regine Delourme, Barry J. Pogson, Sureshkumar Balasubramanian, Rosy Raman   +13 more
wiley   +1 more source

Identification of a novel regulatory mechanism for the disease associated protein, uPAR [PDF]

, 2014
Expression quantitative trait loci (eQTLs), as determined through a series of statistical association studies collectively known as genome-wide association (GWA) studies, have provided us with a hypothesis free approach for the investigation into ...
Hall, Ian P., Portelli, Michael A., Sayers, Ian   +2 more
core  

SNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies

BMC Genetics, 2019
Background Over the relatively short history of Genome Wide Association Studies (GWASs), hundreds of GWASs have been published and thousands of disease risk-associated SNPs have been identified.
Ivan Gorlov, Xiangjun Xiao, Maureen Mayes, Olga Gorlova, Christopher Amos   +4 more
doaj   +1 more source

Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Chronic obstructive pulmonary disease (COPD) is associated with musculoskeletal comorbidities, including cachexia. Weight loss (WL) is the major criterion for cachexia and increases risk for mortality in COPD. Risk factors for WL in COPD are incompletely understood.
Joe W. Chiles III, Alison Rocco, Vinodh Srinivasasainagendra, Harry B. Rossiter, Richard Casaburi, Anna Thalacker‐Mercer, J. Michael Wells, Emily S. Wan, Edwin K. Silverman, Michael H. Cho, Craig P. Hersh, Bruce M. Psaty, Sina A. Gharib, Yan Gao, George T. O'Connor, Leslie A. Lange, Stephen S. Rich, Ani W. Manichaikul, R. Graham Barr, Victor E. Ortega, Deborah A. Meyers, Albert V. Smith, Hemant K. Tiwari, Merry‐Lynn N. McDonald   +23 more
wiley   +1 more source

OneK1K pseudobulk eQTL dataset

, 2023
OneK1K
openaire   +1 more source

Bayes factor for linear mixed model in genetic association studies

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Bayes factor has advantages over p‐value as test statistics for association, particularly when comparing multiple non‐nested alternative models. An efficient method to compute Bayes factor for linear mixed model (LMM) in the context of genetic association studies is lacking.
Yongtao Guan, Daniel Levy
wiley   +1 more source

eQTLs in platelets and iPSC-megakaryocytes [PDF]

Blood, 2021
Elizabeth A, Middleton, Jesse W, Rowley
openaire   +2 more sources

Heterokairic Genes and the Eco‐Evo‐Devo of Timing

Evolution &Development, Volume 28, Issue 2, June 2026.
Heterokairic genes as the bridge (Heterokairic Pathways?): Heterokairic genes are heterochronic regulators whose activity is modulated by environmental conditions. External cues (e.g., temperature, nutrition, oxygen, density: yellow box) are sensed (yellow arrows) and converted into endocrine and metabolic signals (purple box and arrow into fish's ...
Leandro Lofeu, Ehsan Pashay Ahi
wiley   +1 more source