Results 151 to 160 of about 48,393 (270)
Immunology, Volume 178, Issue 2, Page 280-292, June 2026.A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan +14 more
wiley +1 more source
Landscape of stimulation-responsive chromatin across diverse human immune cells. [PDF]
, 2019 A hallmark of the immune system is the interplay among specialized cell types transitioning between resting and stimulated states. The gene regulatory landscape of this dynamic system has not been fully characterized in human cells.
Anderson, Mark S +19 more
core
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION Alzheimer's disease (AD) is a heterogeneous disease with diverse disease progression trajectories and brain pathology. Identifying AD subtypes is essential for understanding AD etiology, heterogeneity, and developing precise treatment. METHODS We applied a subspace‐merging algorithm to integrate multi‐omics data from brain tissues
Ziyan Song +5 more
wiley +1 more source
The use of general and specific combining abilities in a context of gene expression relevant to plant breeding [PDF]
Many common traits are believed to be a composite reflection of multiple genetic and environmental factors. Recent advances suggest that subtle variations in the regulation of gene expression may contribute to quantitative traits.
Eeuwijk, F.A., van, Vuylsteke, M.
core +2 more sources
Integrating polygenic and transcriptional risk scores for detecting Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION Early detection of Alzheimer's disease (AD) is essential, yet existing biomarkers are invasive or costly. Polygenic risk scores (PRS) and transcriptional risk scores (TRS) may offer accessible alternatives, but their combined predictive performance remains understudied.
Jiyun Hwang +10 more
wiley +1 more source
Unsupervised empirical Bayesian multiple testing with external covariates
, 2008 In an empirical Bayesian setting, we provide a new multiple testing method, useful when an additional covariate is available, that influences the probability of each null hypothesis being true.
Ferkingstad, Egil +4 more
core +2 more sources
The genetic architecture of gene expression levels in wild baboons
eLife, 2015 Primate evolution has been argued to result, in part, from changes in how genes are regulated. However, we still know little about gene regulation in natural primate populations.
Jenny Tung +4 more
doaj +1 more source
Maternal Chrono‐Nutrition and Placental DNA Methylation: The BiSC Study
Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.This is the first study to examine how the timing of a mother's meals during pregnancy relates to changes in placental DNA methylation, an epigenetic mark. We found that the timing of the last daily meal was most important. Some epigenetic changes were linked to genes involved in placental function and development, and the long‐term health consequences
Joana Llauradó‐Pont +12 more
wiley +1 more source
Aging Cell, Volume 25, Issue 5, May 2026.We developed a LASSO‐based approach to uncover a three‐layered “fan‐in fan‐out” network architecture for complex traits like yeast aging, showing that peripheral genes influence lifespan indirectly through master regulators, which converge on core functional modules (e.g., stress response, autophagy).
Meng Ma +12 more
wiley +1 more source