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Tissue-Specific eQTL in Zebrafish
2019Copy number variants (CNVs) refer to the loss or gain of copies of a genomic DNA region. While some CNVs may play a role in species evolution by enriching the diversity of an organism, CNVs may also be linked to certain diseases such as neurological disorders, early onset obesity, and cancer.
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Introductory Methods for eQTL Analyses
2019Expression quantitative trait locus (eQTL) analysis has proven to be a powerful method to describe how variation in phenotypes may be attributed to a given genotype. While the field of bioinformatics and genomics has experienced exponential growth with modern technological advances, an unintended consequence arises as a lack of a gold standard for many
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eQTL Analysis in Mice and Rats
2009Since the introduction of genetical genomics in 2001, many studies have been published on various organisms, including mouse and rat. Genetical genomics makes use of the latest microarray profiling technologies and combines vast amounts of genotype and gene expression information, a strategy that has proven very successful in inbred line crosses.
Tesson, B. M., Jansen, R. C.
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eQTL's in Prakriti replicated SNPs
2019قائمة براكريتي المكررة SNPs بمثابة eQTL في أنسجة ...
Tahseen Abbas +3 more
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Distributed eQTL analysis with auxiliary information
Journal of Statistical Planning and InferenceExpression quantitative trait locus (eQTL) analysis is a useful tool to identify genetic loci that are associated with gene expression levels. Large collaborative efforts such as the Genotype-Tissue Expression (GTEx) project provide valuable resources for eQTL analysis in different tissues.
Fang, Zhiwen +4 more
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2019
Expression quantitative trait loci (eQTL) mapping studies identify genetic loci that regulate gene expression. eQTL mapping studies can capture gene regulatory interactions and provide insight into the genetic mechanism of biological systems. Recently, the integration of multi-omics data, such as single-nucleotide polymorphisms (SNPs), copy number ...
Kang, Mingon, Gao, Jean
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Expression quantitative trait loci (eQTL) mapping studies identify genetic loci that regulate gene expression. eQTL mapping studies can capture gene regulatory interactions and provide insight into the genetic mechanism of biological systems. Recently, the integration of multi-omics data, such as single-nucleotide polymorphisms (SNPs), copy number ...
Kang, Mingon, Gao, Jean
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Inferring Molecular Interactions Pathways from eQTL Data
2009Analysis of expression quantitative trait loci (eQTL) helps elucidate the connection between genotype, gene expression levels, and phenotype. However, standard statistical genetics can only attribute the changes in expression levels to loci on the genome, not specific genes.
Imran, Rashid +2 more
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